프랑수아 자코브

위키백과, 우리 모두의 백과사전.
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François Jacob
1965년
1965년
출생 1920년 6월 17일(1920-06-17)[1]
프랑스 낭시
사망 2013년 4월 19일 (92세)[1]
프랑스 파리
국적 프랑스
분야 병리학
유전학
출신 대학 파리 대학교
주요 업적 오페론[2][3]
수상 Grand Prix Charles-Leopold Mayer(1962년)
노벨 생리학·의학상(1965년)
ForMemRS(1973년)[4]
한스 크레브스 경 메달(영어판)(1982년)

프랑수아 자코브(프랑스어: François Jacob, ForMemRS[4], 1920년 6월 17일 ~ 2013년 4월 19일)는 프랑스병리학자, 유전학자이다. 1965년에 효소의 유전적 조절 작용과 바이러스 합성에 대한 연구로 앙드레 르보프, 자크 모노와 함께 노벨 생리학·의학상을 수상했다.[1][5][6][4]

수상 경력[편집]

회원[편집]

서적[편집]

  • Jacob, François; E. L. Wollman. Sexuality and the Genetics of Bacteria. Academic Press, 1961 OCLC 251900319
  • Jacob, François. The Possible & The Actual. Pantheon Books, 1982 ISBN 9780295958880
  • Jacob, François. The Statue Within: An Autobiography by, translated from the 1987 French edition by Franklin Philip. Basic Books, 1988. ISBN 978-0-465-08223-0; new edition: 9780879694760
  • Jacob, François. The Logic of Life. translated from the 1976 French edition by Princeton University Press, 1993 ISBN 0394472462
  • Jacob, François. Of Flies, Mice and Men, translated from the French edition and published by Harvard University Press, 1998 ISBN 9780674631113
  • Jacob, F.; Perrin, D.; Sánchez, C.; Monod, J.; Edelstein, S. (2005). “The operon: A group of genes with expression coordinated by an operator. C.R.Acad. Sci. Paris 250 (1960) 1727–1729”. 《Comptes rendus biologies》 328 (6): 514–520. PMID 15999435. doi:10.1016/j.crvi.2005.04.005. 
  • Ullmann, A.; Jacob, F.; Monod, J. (1968). “On the subunit structure of wild-type versus complemented beta-galactosidase of Escherichia coli”. 《Journal of Molecular Biology》 32 (1): 1–13. PMID 4868117. doi:10.1016/0022-2836(68)90140-X. 
  • Ullmann, A.; Jacob, F.; Monod, J. (1967). “Characterization by in vitro complementation of a peptide corresponding to an operator-proximal segment of the beta-galactosidase structural gene of Escherichia coli”. 《Journal of Molecular Biology》 24 (2): 339–343. PMID 5339877. doi:10.1016/0022-2836(67)90341-5. 
  • Ullmann, A.; Perrin, D.; Jacob, F.; Monod, J. (1965). “Identification, by in vitro complementation and purification, of a peptide fraction of Escherichia coli beta-galactosidase”. 《Journal of Molecular Biology》 12 (3): 918–923. PMID 4285628. doi:10.1016/S0022-2836(65)80338-2. 
  • Willson, C.; Perrin, D.; Cohn, M.; Jacob, F.; Monod, J. (1964). “Non-Inducible Mutants of the Regulator Gene in the "lactose" System of Escherichia Coli”. 《Journal of Molecular Biology》 8 (4): 582–592. PMID 14153528. doi:10.1016/S0022-2836(64)80013-9. 
  • Jacob, F.; Ullman, A.; Monod, J. (1964). “The Promotor, A Genetic Element Necessary to the Expression of an Operon”. 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 258: 3125–3128. PMID 14143651. 
  • Jacob, F.; Monod, J. (1964). “Biochemical and Genetic Mechanisms of Regulation in the Bacterial Cell”. 《Bulletin de la Societe de chimie biologique》 46: 1499–1532. PMID 14270538. 
  • Monod, J.; Changeux, J.; Jacob, F. (1963). “Allosteric proteins and cellular control systems”. 《Journal of Molecular Biology》 6 (4): 306–329. PMID 13936070. doi:10.1016/S0022-2836(63)80091-1. 
  • Jacob, F.; Sussman, R.; Monod, J. (1962). “On the nature of the repressor ensuring the immunity of lysogenic bacteria”. 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 254: 4214–4216. PMID 14036499. 
  • Jacob, F.; Monod, J. (1961). “Genetic regulatory mechanisms in the synthesis of proteins”. 《Journal of Molecular Biology》 3 (3): 318–356. PMID 13718526. doi:10.1016/S0022-2836(61)80072-7. 
  • Monod, J.; Jacob, F. (1961). “Teleonomic mechanisms in cellular metabolism, growth, and differentiation”. 《Cold Spring Harbor symposia on quantitative biology》 26: 389–401. PMID 14475415. doi:10.1101/sqb.1961.026.01.048. 
  • Perrin, D.; Jacob, F.; Monod, J. (1960). “Induced biosynthesis of a genetically modified protein not presenting affinity for the inductor”. 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 251: 155–157. PMID 13734531. 
  • Buttin, G.; Jacob, F.; Monod, J. (1960). “Constituent synthesis of galactokinase following the development of lambda bacteriophages in Escherichia coli K 12”. 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 250: 2471–2473. PMID 13806544. 
  • Jacob, F.; Perrin, D.; Sánchez, C.; Monod, J. (February 1960). “L'opéron : groupe de gènes à expression coordonnée par un opérateur” [Operon: a group of genes with the expression coordinated by an operator] (PDF). 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 (Facsimile version reprinted in 2005) 250 (6): 1727–1729. ISSN 0001-4036. PMID 14406329. 
  • Jacob, F.; Monod, J. (1959). “Genes of structure and genes of regulation in the biosynthesis of proteins”. 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 249: 1282–1284. PMID 14406327. 
  • Pardee, A.; Jacob, F.; Monod, J. (1958). “The role of the inducible alleles and the constitutive alleles in the synthesis of beta-galactosidase in zygotes of Escherichia coli”. 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 246 (21): 3125–3128. PMID 13547552. 
  • Jacob, F.; Torriani, A.; Monod, J. (1951). “Effect of ultraviolet rays on the biosynthesis of galactosidase and on the multiplication of T2 bacteriophage in Escherichia coli”. 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 233 (20): 1230–1232. PMID 14905606. 

각주[편집]

  1. Morange, Michel (2013). “François Jacob (1920–2013) French freedom fighter who helped to uncover how genes are regulated”. 《Nature》 497 (7450): 440. Bibcode:2013Natur.497..440M. PMID 23698437. doi:10.1038/497440a. 
  2. Jacob, F.; Perrin, D.; Sánchez, C.; Monod, J. (February 1960). “L'opéron : groupe de gènes à expression coordonnée par un opérateur” [Operon: a group of genes with the expression coordinated by an operator] (PDF). 《Comptes rendus hebdomadaires des seances de l'Academie des sciences》 (Facsimile version reprinted in 2005) 250 (6): 1727–1729. ISSN 0001-4036. PMID 14406329. 
  3. Jacob, F. O. (2011). “The Birth of the Operon”. 《Science》 332 (6031): 767–767. Bibcode:2011Sci...332..767J. PMID 21566161. doi:10.1126/science.1207943. 
  4. Morange, Michel (2017). “François Jacob. 17 June 1920 – 19 April 2013”. 《Biographical Memoirs of Fellows of the Royal Society》 (London: Royal Society): rsbm20160021. ISSN 0080-4606. doi:10.1098/rsbm.2016.0021. 
  5. Jacob, F.; Girard, M. (1998). “Andre Michel Lwoff. 8 May 1902–30 September 1994”. 《Biographical Memoirs of Fellows of the Royal Society》 44: 255–263. ISSN 0080-4606. PMID 11623983. doi:10.1098/rsbm.1998.0017. 
  6. “Nobel-winning biologist Francois Jacob dies at 92”. The Raw Story. 2013년 4월 22일에 확인함. 

외부 링크[편집]

위키미디어 공용에 프랑수아 자코브 관련 미디어 분류가 있습니다.