GRIP1

GRIP1
사용 가능한 구조
PDB	동원체 검색: PDBe RCSB
PDB ID 코드 목록
	2JIL
식별자
다른 이름	GRIP1, GRIP, glutamate receptor interacting protein 1, FRASRS3
외부 ID	OMIM: 604597 MGI: 1921303 HomoloGene: 12938 GeneCards: GRIP1
유전자 위치 (인간)
염색체	12번 염색체
끝	67,069,162 bp
유전자 위치 (쥐)
염색체	10번 염색체 (쥐)
끝	119,923,166 bp
RNA 발현 패턴
	최상위 발현
	ganglionic eminence; ; 정낭; ; secondary oocyte; ; 배의 피부; ; 태반; ; 오른자궁관; ; 내피세포; ; 작은침샘; ; left lobe of thyroid gland; ; 전전두엽피질;
	최상위 발현
	spermatid; ; 세정관; ; habenula; ; secondary oocyte; ; olfactory bulb; ; barrel cortex; ; 운동 신경 세포; ; 솔방울샘; ; ganglionic eminence; ; trigeminal ganglion;
	추가 참조 발현 데이터
	추가 참조 발현 데이터
유전자 온톨로지
분자 함수	beta-catenin binding; transcription coactivator activity; protein C-terminus binding; 단백질 결합; androgen receptor binding; glucocorticoid receptor binding; signaling receptor complex adaptor activity;
세포 성분	recycling endosome; 세포액; postsynaptic membrane; 세포막; 세포막; 연접; 세포연접; 수상돌기; 소포체; 지질뗏목; neuron projection; cytoplasmic vesicle; glutamatergic synapse;
생물학적 과정	protein localization; androgen receptor signaling pathway; intracellular signal transduction; dendrite development; positive regulation of transcription, DNA-templated; neurotransmitter receptor transport, endosome to postsynaptic membrane; vesicle-mediated transport in synapse; positive regulation of neuron projection arborization; positive regulation of signal transduction;
	출처: Amigo / QuickGO
동원체
	23426
	74053
	ENSG00000155974
	ENSMUSG00000034813
	Q9Y3R0
	Q925T6
NM_001178074; NM_021150; NM_001366722; NM_001366723; NM_001366724;
	NM_001379345; NM_001379346; NM_001379347; NM_001379348; NM_001379349; NM_001379351
NM_001277292; NM_001277293; NM_001277294; NM_001277295; NM_028736;
	NM_130891; NM_133442; NM_001358809; NM_001358810; NM_001358811
NP_001171545; NP_066973; NP_001353651; NP_001353652; NP_001353653;
	NP_001366274; NP_001366275; NP_001366276; NP_001366277; NP_001366278; NP_001366280
NP_001264221; NP_001264222; NP_001264223; NP_001264224; NP_083012;
	NP_570961; NP_597699; NP_001345738; NP_001345739; NP_001345740
	위키데이터
인간 보기/편집	쥐 보기/편집

글루탐산 수용체 상호 작용 단백질 1(Glutamate receptor-interacting protein 1)은 인간에서 GRIP1 유전자 의해 암호화되는 단백질이다.^[5]^[6]

상호 작용[편집]

GRIP1은 다음과 상호 작용 하는 것으로 나타났다.

GRM3
GRIA2
GRIA3
GRIA4^[7]
GRIK2^[8]
GRIK3^[9]

각주[편집]

↑ ^가 ^나 ^다 GRCh38: Ensembl release 89: ENSG00000155974 - 앙상블, May 2017
↑ ^가 ^나 ^다 GRCm38: Ensembl release 89: ENSMUSG00000034813 - 앙상블, May 2017
↑ “Human PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.
↑ “Mouse PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.
↑ “EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains”. 《Neuron》 22 (3): 511–24. April 1999. doi:10.1016/S0896-6273(00)80706-0. PMID 10197531.
↑ “Entrez Gene: GRIP1 glutamate receptor interacting protein 1”.
↑ “The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs”. 《J. Biol. Chem.》 277 (18): 15221–4. May 2002. doi:10.1074/jbc.C200112200. PMID 11891216.
↑ “Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP”. 《Neuron》 37 (4): 625–38. February 2003. doi:10.1016/S0896-6273(02)01191-1. PMC 3314502. PMID 12597860.
↑ “GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex”. 《Neuron》 26 (3): 603–17. June 2000. doi:10.1016/S0896-6273(00)81198-8. PMID 10896157.

[refGRCh38Ensembl-1] 가 ^나 ^다 GRCh38: Ensembl release 89: ENSG00000155974 - 앙상블, May 2017

[refGRCm38Ensembl-2] 가 ^나 ^다 GRCm38: Ensembl release 89: ENSMUSG00000034813 - 앙상블, May 2017

[3] “Human PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.

[4] “Mouse PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.

[pmid10197531-5] “EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains”. 《Neuron》 22 (3): 511–24. April 1999. doi:10.1016/S0896-6273(00)80706-0. PMID 10197531.

[entrez-6] “Entrez Gene: GRIP1 glutamate receptor interacting protein 1”.

[pmid11891216-7] “The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs”. 《J. Biol. Chem.》 277 (18): 15221–4. May 2002. doi:10.1074/jbc.C200112200. PMID 11891216.

[pmid12597860-8] “Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP”. 《Neuron》 37 (4): 625–38. February 2003. doi:10.1016/S0896-6273(02)01191-1. PMC 3314502. PMID 12597860.

[pmid10896157-9] “GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex”. 《Neuron》 26 (3): 603–17. June 2000. doi:10.1016/S0896-6273(00)81198-8. PMID 10896157.

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