분자 인식

분자 인식(分子認識, 영어: molecular recognition)이라는 용어는 수소 결합, 금속 배위, 소수성 힘,^[2]^[3] 반데르발스 힘, π-π 상호작용, 할로젠 결합 또는 공명 상호작용^[4] 효과와 같은 비공유결합성 상호작용을 통해 두 개 이상의 분자 사이의 특정 상호작용을 나타낸다. 이러한 직접적인 상호작용 외에도 용매는 용액에서 분자 인식을 유도하는 데 지배적이고 간접적인 역할을 할 수 있다.^[5]^[6] 분자 인식에 관여하는 호스트와 게스트는 분자 상보성(分子相補性, 영어: molecular complementarity)을 나타낸다. 포털이 본질적으로 선택성을 제어하는 나노튜브를 포함한^[7]^[8]^[9]^[10] 분자 용기는 예외이다.^[11]^[12]

같이 보기[편집]

분자

각주[편집]

↑ Knox JR, Pratt RF (July 1990). “Different modes of vancomycin and D-alanyl-D-alanine peptidase binding to cell wall peptide and a possible role for the vancomycin resistance protein” (Free full text). 《Antimicrobial Agents and Chemotherapy》 34 (7): 1342–1347. doi:10.1128/AAC.34.7.1342. PMC 175978. PMID 2386365.
↑ Lockett MR, Lange H, Breiten B, Heroux A, Sherman W, Rappoport D, 외. (July 2013). “The binding of benzoarylsulfonamide ligands to human carbonic anhydrase is insensitive to formal fluorination of the ligand”. 《Angewandte Chemie》 52 (30): 7714–7717. doi:10.1002/anie.201301813. PMID 23788494. S2CID 1543705.
↑ Breiten B, Lockett MR, Sherman W, Fujita S, Al-Sayah M, Lange H, 외. (October 2013). “Water networks contribute to enthalpy/entropy compensation in protein-ligand binding”. 《Journal of the American Chemical Society》 135 (41): 15579–15584. CiteSeerX 10.1.1.646.8648. doi:10.1021/ja4075776. PMID 24044696. S2CID 17554787.
↑ Cosic I (December 1994). “Macromolecular bioactivity: is it resonant interaction between macromolecules?--Theory and applications”. 《IEEE Transactions on Bio-Medical Engineering》 41 (12): 1101–1114. doi:10.1109/10.335859. PMID 7851912. S2CID 23892544.
↑ Baron R, Setny P, McCammon JA (September 2010). “Water in cavity-ligand recognition”. 《Journal of the American Chemical Society》 132 (34): 12091–12097. doi:10.1021/ja1050082. PMC 2933114. PMID 20695475.
↑ Baron R, McCammon JA (2013). “Molecular recognition and ligand association”. 《Annual Review of Physical Chemistry》 64: 151–175. Bibcode:2013ARPC...64..151B. doi:10.1146/annurev-physchem-040412-110047. PMID 23473376.
↑ Lehn JM (1995). 《Supramolecular Chemistry》. Weinheim: Wiley-VCH. ISBN 978-3-527-29312-4. OCLC 315928178.
↑ Gellman SH (August 1997). “Introduction: Molecular Recognition”. 《Chemical Reviews》 97 (5): 1231–1232. doi:10.1021/cr970328j. PMID 11851448.
↑ Chatterji D (2016). 《Basics of Molecular Recognition》. Boca Raton, FL: CRC Press. ISBN 978-1-4822-1968-5.
↑ Rotello V, Thayumanavan S, 편집. (2008). 《Molecular recognition and polymers : control of polymer structure and self-assembly》. Hoboken, N.J.: Wiley. ISBN 978-0-470-27738-6.
↑ Cram DJ, Cram JM (1997). 《Container molecules and their guests》. Cambridge: Royal Society of Chemistry. ISBN 978-0-85186-972-8.
↑ Brotin T, Dutasta JP (January 2009). “Cryptophanes and their complexes--present and future”. 《Chemical Reviews》 109 (1): 88–130. doi:10.1021/cr0680437. PMID 19086781.

외부 링크[편집]

“Special Issue on Molecular Recognition”. 《International Journal of Molecular Sciences》.

[1] Knox JR, Pratt RF (July 1990). “Different modes of vancomycin and D-alanyl-D-alanine peptidase binding to cell wall peptide and a possible role for the vancomycin resistance protein” (Free full text). 《Antimicrobial Agents and Chemotherapy》 34 (7): 1342–1347. doi:10.1128/AAC.34.7.1342. PMC 175978. PMID 2386365.

[2] Lockett MR, Lange H, Breiten B, Heroux A, Sherman W, Rappoport D, 외. (July 2013). “The binding of benzoarylsulfonamide ligands to human carbonic anhydrase is insensitive to formal fluorination of the ligand”. 《Angewandte Chemie》 52 (30): 7714–7717. doi:10.1002/anie.201301813. PMID 23788494. S2CID 1543705.

[3] Breiten B, Lockett MR, Sherman W, Fujita S, Al-Sayah M, Lange H, 외. (October 2013). “Water networks contribute to enthalpy/entropy compensation in protein-ligand binding”. 《Journal of the American Chemical Society》 135 (41): 15579–15584. CiteSeerX 10.1.1.646.8648. doi:10.1021/ja4075776. PMID 24044696. S2CID 17554787.

[4] Cosic I (December 1994). “Macromolecular bioactivity: is it resonant interaction between macromolecules?--Theory and applications”. 《IEEE Transactions on Bio-Medical Engineering》 41 (12): 1101–1114. doi:10.1109/10.335859. PMID 7851912. S2CID 23892544.

[5] Baron R, Setny P, McCammon JA (September 2010). “Water in cavity-ligand recognition”. 《Journal of the American Chemical Society》 132 (34): 12091–12097. doi:10.1021/ja1050082. PMC 2933114. PMID 20695475.

[6] Baron R, McCammon JA (2013). “Molecular recognition and ligand association”. 《Annual Review of Physical Chemistry》 64: 151–175. Bibcode:2013ARPC...64..151B. doi:10.1146/annurev-physchem-040412-110047. PMID 23473376.

[7] Lehn JM (1995). 《Supramolecular Chemistry》. Weinheim: Wiley-VCH. ISBN 978-3-527-29312-4. OCLC 315928178.

[8] Gellman SH (August 1997). “Introduction: Molecular Recognition”. 《Chemical Reviews》 97 (5): 1231–1232. doi:10.1021/cr970328j. PMID 11851448.

[9] Chatterji D (2016). 《Basics of Molecular Recognition》. Boca Raton, FL: CRC Press. ISBN 978-1-4822-1968-5.

[10] Rotello V, Thayumanavan S, 편집. (2008). 《Molecular recognition and polymers : control of polymer structure and self-assembly》. Hoboken, N.J.: Wiley. ISBN 978-0-470-27738-6.

[11] Cram DJ, Cram JM (1997). 《Container molecules and their guests》. Cambridge: Royal Society of Chemistry. ISBN 978-0-85186-972-8.

[12] Brotin T, Dutasta JP (January 2009). “Cryptophanes and their complexes--present and future”. 《Chemical Reviews》 109 (1): 88–130. doi:10.1021/cr0680437. PMID 19086781.

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