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--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------[{to[selfcom auto make made]config}~(from admination write anwser requier)]:(to main cpu puzzle quiz quest[{[solve requier admination:(per[{descript special simbol}per account])quiz quest}])~(from admination{requier post send}solve)}]:main cpu process processign(to first forword post{send[(admin{adual})}admination)]}~{from include order quize puzzle}:anwser solve{requier admination}]]:({[(edit field or round)open file]adapt or boot advence menu)}direct dynamice deviect drive kind}={to[<!--[if !vml]-->{(yes[{<{selfcom parser auto chooice[{[]}]}>no])}~from([([none write area:air and none rewirte or none patch]+{none disk copy} or {none include order}index):{[<!--[endif]-->]:ducommend}]):({[solve or quest]:main cpu process processign anwser or admination solve requier anwser})
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}={to[<!--[if !vml]-->{(yes[{<{selfcom parser auto chooice[{[]}]}>no])}=([([none write area:air and none rewirte or none patch]+{none disk copy} or {none include order}index):{[<!--[endif]-->]:ducommend}])
[logical selfcom parser(message loop luff load loding[Get{Setting}Project by Email{Get Projects by RSS:(Post{send})}])]
[logical selfcom parser(message loop luff load loding[Get{Setting}Project by Email{Get Projects by RSS:(Post{send})}])]+{[The evolution of bread(boards)]field+round}
[logical selfcom parser(message loop luff load loding[Get{Setting}Project by Email{Get Projects by RSS:(Post{send})}])]+{[The evolution of bread(boards)]field+round}+(First forword[none eae{effect or empact or affect}]eae)+({move play in white board}script cell:sell)
[logical selfcom parser(message loop luff load loding[Get{Setting}Project by Email{Get Projects by RSS:(Post{send})}])]+{[The evolution of bread(boards)]field+round}+(First forword[none eae{effect or empact or affect}]eae)+({move play in white board}script cell:sell)+({move runtim changed}+measure+temp{abs})
[logical selfcom parser(message loop luff load loding[Get{Setting}Project by Email{Get Projects by RSS:(Post{send})}])]+{[The evolution of bread(boards)]field+round}+(First forword[none eae{effect or empact or affect}]eae)+({move play in white board}script cell:sell)+{faced with choices like even get me started on Panera}+{The board industry naturally followed sheat}cell:[sell move change limit(oma<=>tran)] with (board of [all shake sizes and color]selfcom parser)
[logical selfcom parser(message loop luff load loding[Get{Setting}Project by Email{Get Projects by RSS:(Post{send})}])]+{[The evolution of bread(boards)]field+round}+(First forword[none eae{effect or empact or affect}]eae)+({move play in white board}script cell:sell)+{faced with choices like even get me started on Panera}+{The board industry naturally followed sheat}cell:[sell move change limit(oma<=>tran)] with (board of [all shake sizes and color]selfcom parser)=(In particular{pallete+culcalleration})+(loading[remember when we launched]connect config)
[logical selfcom parser(message loop luff load loding[Get{Setting}Project by Email{Get Projects by RSS:(Post{send})}])]+{[The evolution of bread(boards)]field+round}+(First forword[none eae{effect or empact or affect}]eae)+({move play in white board}script cell:sell)+{faced with choices like even get me started on Panera}+{The board industry naturally followed sheat}cell:[sell move change limit(oma<=>tran)] with (board of [all shake sizes and color]selfcom parser)=(In particular{pallete+culcalleration})+(loading[remember when we launched]connect config)+([to min~from Mini~next many~next far more many~next fal fall move most many]):[{sell:xell point position({Proto[Board]}script screen board:box board type)}]
[logical selfcom parser(message loop luff load loding[Get{Setting}Project by Email{Get Projects by RSS:(Post{send})}])]+{[The evolution of bread(boards)]field+round}+(First forword[none eae{effect or empact or affect}]eae)+({move play in white board}script cell:sell)+{faced with choices like even get me started on Panera}+{The board industry naturally followed sheat}cell:[sell move change limit(oma<=>tran)] with (board of [all shake sizes and color]selfcom parser)=(In particular{pallete+culcalleration})+(loading[remember when we launched]connect config)+([to min~from Mini~next many~next far more many~next fal fall move most many]):[{sell:xell point position({Proto[Board]}script screen board:box board type)}]={([alternative(order[pexcel:pixell])abs]) or keremargency}+({boll holl bunch at once})
[logical selfcom parser(message loop luff load loding[Get{Setting}Project by Email{Get Projects by RSS:(Post{send})}])]+{[The evolution of bread(boards)]field+round}+(First forword[none eae{effect or empact or affect}]eae)+({move play in white board}script cell:sell)+{faced with choices like even get me started on Panera}+{The board industry naturally followed sheat}cell:[sell move change limit(oma<=>tran)] with (board of [all shake sizes and color]selfcom parser)=(In particular{pallete+culcalleration})+(loading[remember when we launched]connect config)+([to min~from Mini~next many~next far more many~next fal fall move most many]):[{sell:xell point position({Proto[Board]}script screen board:box board type)}]={([alternative(order[pexcel:pixell])abs]) or keremargency}+({boll holl bunch at once})+[creativity]:[(defence area air crash or fusion)+([your project]periad or periad{bend}:fusion)]=(selfcom only make made auto play[it is fun either way])
[logical selfcom parser(message loop luff load loding[Get{Setting}Project by Email{Get Projects by RSS:(Post{send})}])]+{[The evolution of bread(boards)]field+round}+(First forword[none eae{effect or empact or affect}]eae)+({move play in white board}script cell:sell)+{faced with choices like even get me started on Panera}+{The board industry naturally followed sheat}cell:[sell move change limit(oma<=>tran)] with (board of [all shake sizes and color]selfcom parser)=(In particular{pallete+culcalleration})+(loading[remember when we launched]connect config)+([to min~from Mini~next many~next far more many~next fal fall move most many]):[{sell:xell point position({Proto[Board]}script screen board:box board type)}]={([alternative(order[pexcel:pixell])abs]) or keremargency}+({boll holl bunch at once})+[creativity]:[(defence area air crash or fusion)+([your project]periad or periad{bend}:fusion)]=(selfcom only make made auto play[it is fun either way]) or as min~mini~many~more~most as demention extence board make made another or other black protoboard=[dark grass board]
[logical selfcom parser(message loop luff load loding[Get{Setting}Project by Email{Get Projects by RSS:(Post{send})}])]+{[The evolution of bread(boards)]field+round}+(First forword[none eae{effect or empact or affect}]eae)+({move play in white board}script cell:sell)+{faced with choices like even get me started on Panera}+{The board industry naturally followed sheat}cell:[sell move change limit(oma<=>tran)] with (board of [all shake sizes and color]selfcom parser)=(In particular{pallete+culcalleration})+(loading[remember when we launched]connect config)+([to min~from Mini~next many~next far more many~next fal fall move most many]):[{sell:xell point position({Proto[Board]}script screen board:box board type)}]={([alternative(order[pexcel:pixell])abs]) or keremargency}+({boll holl bunch at once})+[creativity]:[(defence area air crash or fusion)+([your project]periad or periad{bend}:fusion)]=(selfcom only make made auto play[it is fun either way]) or as min~mini~many~more~most as demention extence board make made another or other black protoboard=[dark grass board]={[Post{send}]:(commend:command{selfcom parser}auto make made)}
logical{[Post{send}]:(commend:command{selfcom parser}auto make made)}={[browser instell induct domain(none allow or none follow)defence include boxtype font or number]message loop luff loading)VMW}CONNECT CONFIG={selfcom parser[Email{ADDRESS HOOKER GOTO WHITE HEAKER:link]}]={TO[http//:www.MicroEntertainmant.com_kr_ko/{[!Shake]set}/(box type{order})]~(FROM TwitterShare to FacebookShare to Pinterest)INTER CONFIG}
logical{[Post{send}]:(commend:command{selfcom parser}auto make made)}={[browser instell induct domain(none allow or none follow)defence include boxtype font or number]message loop luff loading)VMW}CONNECT CONFIG={selfcom parser[Email{ADDRESS HOOKER GOTO WHITE HEAKER:link]}]=[USED{[Label:Liquidware]}]={TO[http//:www.MicroEntertainmant.com_kr_ko/{[!Shake]set}/(box type{order})]~(FROM TwitterShare to FacebookShare to Pinterest)INTER CONFIG}:Label:Liquidware
logical{[Post{send}]:(commend:command{selfcom parser}auto make made)}={[browser instell induct domain(none allow or none follow)defence include boxtype font or number]message loop luff loading)VMW}CONNECT CONFIG={selfcom parser[Email{ADDRESS HOOKER GOTO WHITE HEAKER:link]}]=[USED{[Label:Liquidware]}]={TO[http//:www.MicroEntertainmant.com_kr_ko/{[!Shake]set}/(box type{order})]~(FROM TwitterShare to FacebookShare to Pinterest)INTER CONFIG}:Label:Liquidware={[Community Economic]PAY ROTATION}
logical{[Post{send}]:(commend:command{selfcom parser}auto make made)}={[browser instell induct domain(none allow or none follow)defence include boxtype font or number]message loop luff loading)VMW}CONNECT CONFIG={selfcom parser[Email{ADDRESS HOOKER GOTO WHITE HEAKER:link]}]=[USED{[Label:Liquidware]}]={TO[http//:www.MicroEntertainmant.com_kr_ko/{[!Shake]set}/(box type{order})]~(FROM TwitterShare to FacebookShare to Pinterest)INTER CONFIG}:Label:Liquidware=[BROWSER({TELE:TELL}PHONE)CONFIG)]+{[Community Economic]MEESAGE LOOP PAY ROTATION}:OSH]CONFIG community—economic
logical{[Post{send}]:(commend:command{selfcom parser}auto make made)}={[browser instell induct domain(none allow or none follow)defence include boxtype font or number]message loop luff loading)VMW}CONNECT CONFIG={selfcom parser[Email{ADDRESS HOOKER GOTO WHITE HEAKER:link]}]=[USED{[Label:Liquidware]}]={TO[http//:www.MicroEntertainmant.com_kr_ko/{[!Shake]set}/(box type{order})]~(FROM TwitterShare to FacebookShare to Pinterest)INTER CONFIG}:Label:Liquidware=[BROWSER({TELE:TELL}PHONE)CONFIG)]+{[Community Economic]MEESAGE LOOP PAY ROTATION}:OSH]CONFIG community—economic+{(Community economics are the working{ROTATION DEFENCE}SCOPE:SCORE)RPG GAME SCPE:SCORE USED NUMBER}INCLUDE BOOSTER[{BOOT ADVENCE MENU}BOX AREA AIR SIGNAL(TO{K}~FROM{Z}):POINT POSITION]USED PIN OR WAVE OR VOLUME
logical{[Post{send}]:(commend:command{selfcom parser}auto make made)}={[browser instell induct domain(none allow or none follow)defence include boxtype font or number]message loop luff loading)VMW}CONNECT CONFIG={selfcom parser[Email{ADDRESS HOOKER GOTO WHITE HEAKER:link]}]=[USED{[Label:Liquidware]}]={TO[http//:www.MicroEntertainmant.com_kr_ko/{[!Shake]set}/(box type{order})]~(FROM TwitterShare to FacebookShare to Pinterest)INTER CONFIG}:Label:Liquidware=[BROWSER({TELE:TELL}PHONE)CONFIG)]+{[Community Economic]MEESAGE LOOP PAY ROTATION}:OSH]CONFIG community—economic+{(Community economics are the working{ROTATION DEFENCE}SCOPE:SCORE)RPG GAME SCPE:SCORE USED NUMBER}INCLUDE BOOSTER[{BOOT ADVENCE MENU}BOX AREA AIR SIGNAL(TO{K}~FROM{Z}):{(POINT POSITION]USED PIN OR WAVE OR VOLUME:[functional interaction])PUZZLE BOARD MONSTER}=[each play our roles with in the community]+[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]
logical{[Post{send}]:(commend:command{selfcom parser}auto make made)}={[browser instell induct domain(none allow or none follow)defence include boxtype font or number]message loop luff loading)VMW}CONNECT CONFIG={selfcom parser[Email{ADDRESS HOOKER GOTO WHITE HEAKER:link]}]=[USED{[Label:Liquidware]}]={TO[http//:www.MicroEntertainmant.com_kr_ko/{[!Shake]set}/(box type{order})]~(FROM TwitterShare to FacebookShare to Pinterest)INTER CONFIG}:Label:Liquidware=[BROWSER({TELE:TELL}PHONE)CONFIG)]+{[Community Economic]MEESAGE LOOP PAY ROTATION}:OSH]CONFIG community—economic+{(Community economics are the working{ROTATION DEFENCE}SCOPE:SCORE)RPG GAME SCPE:SCORE USED NUMBER}INCLUDE BOOSTER[{BOOT ADVENCE MENU}BOX AREA AIR SIGNAL(TO{K}~FROM{Z}):{(POINT POSITION]USED PIN OR WAVE OR VOLUME:[functional interaction])PUZZLE BOARD MONSTER}=[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=[project oriented OSH communitY]
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=[project oriented OSH communitY]=[engineer and developer can make things even faster and better than previously image]+(puzzle{board monster[defence(move change limit[{show or none show}current])]})]})effect or affect or empact}
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=In this situation, the OSH community not only has the ability to contribute to projects, but also the chance to select and modify the projects they would most like to see. And whatever comes out of this development will not only be high quality and less expensive, but given the grassroots approach, it will also satisfy customer demands more than ever before.
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=The difference between open source hardware and software is that software requires little or no supplies and financial investment—where hardware does. As Matt discussed in an earlier post, the success or failure of OSH depends on what a single individual can achieve within a reasonable personal budget. Based on this, I see two approaches to making OSH successful (i.e., maximizing what each individual can achieve on that budget)
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=1) Incentivize involvement to offset personal financial investment
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=2) Reduce the personal financial investment necessary for development
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=There are different ways to incentivize involvement. But let’s think about open source software. People aren’t paid anything to contribute, and yet the body of software that has been developed is enormous. Look at Linux and Apache. Both have enormous market share—Apache in the realm of 70% (don’t quote me on that). Why? Well, first off, it’s free. But not only is it free, it’s constantly improving. What motivates people to contribute code? As Yological{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=chai Benkler put it in his TED talk on the matter: "Money isn’t always the best motivator…if you leave a $50 check after a dinner with friends, you don't increase the probability of being invited back. And if dinner isn't entirely obvious, think of sex.”
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=His analogy draws a hearty laugh from the audience because they know it’s true. Just because you give someone money does not necessarily make them want to do it more. On the flip side, you could say that they are simply not getting enough money. But the point is that there are things that people will do just for the money, and other things people would choose to do for free because they enjoy them. In the latter category is contributing to open logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=source software.
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=It’s a task that, when farmed out to a large number of people, is nominal work for each person, but they get the satisfaction of contributing to something greater and working with a community of like-minded people. Additionally, contributors will likely be developing something of interest to them, and can each benefit from the community product. Perhaps Ganesh Prasad of Linux Today puts it best:
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=“Metaphorically speaking, each programmer contributes a brick and each gets back a complete house in return. In software, unlike with physical goods, one person's gain does not come at the expense of another because a copy does not deplete the original in any way. Sharing software is not a zero-sum game, and there are tremendous efficiencies from participating in such a cooperative endeavour.”
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=The contributors have numerous non-financial incentives to participate, and their participation does not detract from their lives in any way. The time they spend doing it is enjoyable and gives them a chance to help a community, enriching their lives in both that sense of fulfillment as well as being able to use the end product.
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=But that’s software. So what’s different about open source hardware? Well, the design process can be free and collaborative as with software, but the prototyping and manufacturing of the final product, being tangible, will cost money. As individuals, or even as small groups, it might be difficult to print circuit boards and conduct the prototyping process that is so essential to open-source hardware development. But collectively, it might be worlogical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=thwhile to have prototyping resources available just for developers. And then the open source hardware community could grow and flourish as much as the open source software community currently does. How would this work? Who will make this investment? Matt will speak to these questions in Open Source Hardware, Part 2.
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=Posted by Justin comments Email ThisBlogThis!Share to TwitterShare to FacebookShare to Pinterest
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=Labels: Liquidware
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=Monday, April 21, 2008Putting it all together
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=Here's a quick little video that Chris and I took of the DoubleTall ExenderShield, plus the Arduino, TouchShield, and Lithium BackPack. We've interfaced the whole thing to an accelerometer, and added some bar graph code Mike's been working on.
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=I think it'd be really cool to start a Processing / Wiring graphics API on the TouchShield, so graphics could be programmed in the same API model as the Arduino...
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=And here's another quick video of the same thing:
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=Posted by Matt at 1:37 AM 4 comments Email ThisBlogThis!Share to TwitterShare to FacebookShare to Pinterest
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=Labels: Liquidware
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=Wednesday, April 16, 2008I’d Like the Prime Rib…But Can I Substitute My Baked Potato for a PCB?
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=I was thinking to myself earlier today about the pros and cons of the emergence of open source hardware. I was trying to pin point the details that would make this hobby attractive or make its development distasteful in the view of a very critical and hard-to-impress global society.
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=We find ourselves changing interpretations of certain things all the time. Whether it involves defining what is ethical, fun, interesting, or difficult, it seems we all view aspects of life in a different light. For the sake of agreement, and for the sake of coming to a conclusion for once in our lives, I think it is safe to establish a few maxims concerning open source hardware. In order to establish and preserve the sanctity of open source harlogical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=dware, it is important that we all respect the same underlying principles. In order for a piece of equipment to be considered open source hardware, it must be ready and available to be manipulated by other parties. This type of hardware is so unique because modifications can easily be made to pieces of hardware to either moderately or drastically change the possible functionality of the unit.
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=With this in mind, these modifications can obviously stir up some crazy new ideas and be a vital proponent to the inspiration of innovation. I hope everyone is looking forward to really finding out what the development of open source hardware can mean for global society. Hopefully, researching this development helps widen the minds of engineers, hobbyists, and even those who are new to the concept of open source hardware. This relatively new revlogical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}=olution is showing the world that it is ok to keep imagining. What will your next invention be?
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}={[<!--[if !vml]-->{(yes[{<{selfcom parser auto chooice[{[]}]}>no])}=([none write area:air and none rewirte or none patch]+{none disk copy} or {none include order}index)<!--[endif]-->]:ducommend}
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}={[<!--[if !vml]-->{(yes[{<{selfcom parser auto chooice[{[]}]}>no])}=([none write area:air and none rewirte or none patch]+{none disk copy} or {none include order}index)<!--[endif]-->]:ducommend}+([open source hardware and what are your plan to help shake the open source hardware community]message loop luff loading)+[browser installation tutorial for the Stealth and Slide since it now includes a bunch]
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}={[<!--[if !vml]-->{(yes[{<{selfcom parser auto chooice[{[]}]}>no])}=([none write area:air and none rewirte or none patch]+{none disk copy} or {none include order}index)<!--[endif]-->]:ducommend}+([open source hardware and what are your plan to help shake the open source hardware community]message loop luff loading)+[browser installation tutorial for the Stealth and Slide since it now includes a bunch]+[life live living new message loop SubProcess]={fast graphics function}+{See the updated Up and running}+{on the TouchShield Stealth and Slide in 5 minute}+{where it walks you through the entire installation}
logical{[SELFCOM PARSER{everyone get what they’re looking for—and everyone is better off for it} OR NONE SHOW]=={[for much less than company with huge R&D facility]}=(auto runtime{auto format}selfcom parser server connect or server clude auto format level)=[{[far more in tune]right customer demand}designs and feature]=[{http://WWW.Microsoft.gov.co.kr}:([{({than most company}motioncapture used)none allow or none follow}would be]shell})]=(browser instell config[level only first forword excellent:{top:tap}])={conduct market research to get a sense of what customers want}={[<!--[if !vml]-->{(yes[{<{selfcom parser auto chooice[{[]}]}>no])}=([none write area:air and none rewirte or none patch]+{none disk copy} or {none include order}index)<!--[endif]-->]:ducommend}+([open source hardware and what are your plan to help shake the open source hardware community]message loop luff loading)+(moniter Touch field or round)={browser connect config or boot connect({message loop}email)effect or affect or empact}
logical{[SELFCOM PARSER]}=([{browser connect config or boot connect({message loop}email)effect or affect or empact}point]cell:xell:sell:sill)<=>{({cell:xell:sell:sill}neested need eject enable)keremargency eae first}=({none eae order}eae)=({selfcom parser after}self tree order)={[(as {massege loop} as to your like many{hook or rounter}protocol:protocal)host tcp/ip address assign lisence]}={your probably asking the very valid question which is}=["How the hell do I use this thing?"]
logical{[SELFCOM PARSER]}=([{browser connect config or boot connect({message loop}email)effect or affect or empact}point]cell:xell:sell:sill)<=>{({cell:xell:sell:sill}neested need eject enable)keremargency eae first}=({none eae order}eae)=({selfcom parser after}self tree order)={[(as {massege loop} as to your like many{hook or rounter}protocol:protocal)host tcp/ip address assign lisence]}={your probably asking the very valid question which is}=["How the hell do I use this thing?"]={(edit[message:massege]):{[([area air field or round[Up font or down font]neer or far)and Coding Fast]}updata}
logical{[SELFCOM PARSER]}=([{browser connect config or boot connect({message loop}email)effect or affect or empact}point]cell:xell:sell:sill)<=>{({cell:xell:sell:sill}neested need eject enable)keremargency eae first}=({none eae order}eae)=({selfcom parser after}self tree order)={[(as {massege loop} as to your like many{hook or rounter}protocol:protocal)host tcp/ip address assign lisence]}={your probably asking the very valid question which is}=["How the hell do I use this thing?"]={(edit[message:massege]):{[([area air field or round[Up font or down font]neer or far)and Coding Fast]}updata}=(voicekeyset rimp:ramp[Result+Programming])={(var:bar[Code])all kind expierence}+(vwm[IDE Setup])
logical{[SELFCOM PARSER]}=([{browser connect config or boot connect({message loop}email)effect or affect or empact}point]cell:xell:sell:sill)<=>{({cell:xell:sell:sill}neested need eject enable)keremargency eae first}=({none eae order}eae)=({selfcom parser after}self tree order)={[(as {massege loop} as to your like many{hook or rounter}protocol:protocal)host tcp/ip address assign lisence]}={your probably asking the very valid question which is}=["How the hell do I use this thing?"]={(edit[message:massege]):{[([area air field or round[Up font or down font]neer or far)and Coding Fast]}updata}=(voicekeyset rimp:ramp[Result+Programming])={(var:bar[Code])all kind expierence}
logical{[SELFCOM PARSER]}=([{browser connect config or boot connect({message loop}email)effect or affect or empact}point]cell:xell:sell:sill)<=>{({cell:xell:sell:sill}neested need eject enable)keremargency eae first}=({none eae order}eae)=({selfcom parser after}self tree order)={[(as {massege loop} as to your like many{hook or rounter}protocol:protocal)host tcp/ip address assign lisence]}={your probably asking the very valid question which is}=["How the hell do I use this thing?"]={(edit[message:massege]):{[([area air field or round[Up font or down font]neer or far)and Coding Fast]}updata}=(voicekeyset rimp:ramp[Result+Programming])={(var:bar[Code])all kind expierence}
logical{[SELFCOM PARSER]}=([{browser connect config or boot connect({message loop}email)effect or affect or empact}point]cell:xell:sell:sill)<=>{({cell:xell:sell:sill}neested need eject enable)keremargency eae first}=({none eae order}eae)=({selfcom parser after}self tree order)={[(as {massege loop} as to your like many{hook or rounter}protocol:protocal)host tcp/ip address assign lisence]}={your probably asking the very valid question which is}=["How the hell do I use this thing?"]={(edit[message:massege]):{[([area air field or round[Up font or down font]neer or far)and Coding Fast]}updata}=(voicekeyset rimp:ramp[Result+Programming])={(var:bar[Code])all kind expierence}
logical{[SELFCOM PARSER]}=([{browser connect config or boot connect({message loop}email)effect or affect or empact}point]cell:xell:sell:sill)<=>{({cell:xell:sell:sill}neested need eject enable)keremargency eae first}=({none eae order}eae)=({selfcom parser after}self tree order)={[(as {massege loop} as to your like many{hook or rounter}protocol:protocal)host tcp/ip address assign lisence]}={your probably asking the very valid question which is}=["How the hell do I use this thing?"]={(edit[message:massege]):{[([area air field or round[Up font or down font]neer or far)and Coding Fast]}updata}=(voicekeyset rimp:ramp[Result+Programming])={(var:bar[Code])all kind expierence}=[box name type tree free suggest]
logical{[SELFCOM PARSER]}=([{browser connect config or boot connect({message loop}email)effect or affect or empact}point]cell:xell:sell:sill)<=>{({cell:xell:sell:sill}neested need eject enable)keremargency eae first}=({none eae order}eae)=({selfcom parser after}self tree order)={[(as {massege loop} as to your like many{hook or rounter}protocol:protocal)host tcp/ip address assign lisence]}={your probably asking the very valid question which is}=["How the hell do I use this thing?"]={(edit[message:massege]):{[([area air field or round[Up font or down font]neer or far)and Coding Fast]}updata}=(voicekeyset rimp:ramp[Result+Programming])=[{(var:bar[Code])all kind expierence}=[box name type tree free suggest]:({(add[on/off board])]:cell:xell)oma<=>tran}:{yes<:>no}selfcom parser)
logical{[SELFCOM PARSER]}=([{browser connect config or boot connect({message loop}email)effect or affect or empact}point]cell:xell:sell:sill)=[box name type tree free suggest]:({(add[on/off board])]:cell:xell)oma<=>tran}:{yes<:>no}selfcom parser)designed to be used with an Arduino Diecimila (www.arduino.cc). The TouchShield gives the Arduino an OLED and Touchscreen to help design more advanced applications based around the Arduino electronics development platform.
logical{[SELFCOM PARSER]}=([{browser connect config or boot connect({message loop}email)effect or affect or empact}point]cell:xell:sell:sill)=[box name type tree free suggest]:({(add[on/off board])]:cell:xell)oma<=>tran}:{yes<:>no}selfcom parser)designed to be used with an Arduino Diecimila (www.arduino.cc). The TouchShield gives the Arduino an OLED and Touchscreen to help design more advanced applications based around the Arduino electronics development platform.+[contect Hardware Description]
logical{[SELFCOM PARSER]}=([{browser connect config or boot connect({message loop}email)effect or affect or empact}point]cell:xell:sell:sill)=[box name type tree free suggest]:({(add[on/off board])]:cell:xell)oma<=>tran}:{yes<:>no}selfcom parser)designed to be used with an Arduino Diecimila (www.arduino.cc). The TouchShield gives the Arduino an OLED and Touchscreen to help design more advanced applications based around the Arduino electronics development platform.+[contect Hardware Description]+({([audio+another browser{allow+follow}address assig]={Arduino})}selfcom parser)
logical{[SELFCOM PARSER]}=([{browser connect config or boot connect({message loop}email)effect or affect or empact}point]cell:xell:sell:sill)=[box name type tree free suggest]:({(add[on/off board])]:cell:xell)oma<=>tran}:{yes<:>no}selfcom parser)designed to be used with an Arduino Diecimila (www.arduino.cc). The TouchShield gives the Arduino an OLED and Touchscreen to help design more advanced applications based around the Arduino electronics development platform.+[contect Hardware Description]+({([audio+another browser{allow+follow}address assig]={Arduino})}selfcom parser)+[during programming]
logical{[SELFCOM PARSER]}=([{browser connect config or boot connect({message loop}email)effect or affect or empact}point]cell:xell:sell:sill)=[box name type tree free suggest]:({(add[on/off board])]:cell:xell)oma<=>tran}:{yes<:>no}selfcom parser)designed to be used with an Arduino Diecimila (www.arduino.cc). The TouchShield gives the Arduino an OLED and Touchscreen to help design more advanced applications based around the Arduino electronics development platform.+[contect Hardware Description]+({([audio+another browser{allow+follow}address assig]={Arduino})}selfcom parser)={[beatiful law{[irrigal or error[serial commend]none brance countinue}]}only none connect config browser or boot or adapt connect config]:(none:no[only connect config])}]}
logical{[SELFCOM PARSER]}=([{browser connect config or boot connect({message loop}email)effect or affect or empact}point]cell:xell:sell:sill)=[box name type tree free suggest]:({(add[on/off board])]:cell:xell)oma<=>tran}:{yes<:>no}selfcom parser)designed to be used with an Arduino Diecimila (www.arduino.cc). The TouchShield gives the Arduino an OLED and Touchscreen to help design more advanced applications based around the Arduino electronics development platform.+[contect Hardware Description]+({([audio+another browser{allow+follow}address assig]={Arduino})}selfcom parser)={[beatiful law{[irrigal or error[serial commend]none brance countinue}]}only none connect config browser or boot or adapt connect config]:(none:no[only connect config])}]}=(none:no[between the Arduino and TouchShield are desired. Serials communications are useful when you want to do Input/Output with the Arduino])+logical(Panic Parsed Tools and Factory{[logical(Panic Parsed Tools and Factory{selfcom parser meth add kind[propositon{[Proposition This article is about the term in logic and philosophy. For other uses, see Proposition (disambiguation).
Not to be confused with preposition.+The term proposition has a broad use in contemporary analytic philosophy. It is used to refer to some or all of the following: the primary bearers of truth-value, the objects of belief and other "propositional attitudes" (i.e., what is believed, doubted, etc.), the referents of that-clauses, and the meanings of declarative sentences. Propositions are the sharable objects of attitudes and the primary bearers of truth and falsity. This stipulation rules out certain candidates for propositions, including thought- and utterance-tokens which are not sharable, and concrete events or facts, which cannot be false
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+Computer information presentation
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+Let's make faces with numbers and pixels.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+Watch
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+Let's say Rodi's face monitor is made up of 12 pixels wide and 7 pixels long. Jin wants to make a face for Rodi.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+Below, View uses the principles learned earlier to represent Rodi's smiling face in pixels, and it's a number.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)(If you don't color the first column in each line, we'll first write down the number.)
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+Computer information representation : drawing in binary
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+1. Now make a face for Rodi.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+So what happens to Roddy when you type in the numbers below? Try to color the boxes according to the rules.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+Computer information representation : drawing in binary
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+I'd like to make Rody look like this. What number should I enter?
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+Do you know the difference between a bitmap and a vector?
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+A pixel is a rectangular point, the smallest unit of digital images. In other words, it is also called a "pixel."
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+The higher the number of pixels, the higher the resolution of the image. Resolution means how many small rectangular points are in the image.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+The higher the resolution, the smaller the size and the more pixels you have, the more detailed and clear images you can express.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+However, increasing the resolution is not always a good way because more pixel information to store increases the file's capacity.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+This painting of pixels is called a "bit image." Bitmap is a combination of bits and maps, which means "map of bits."
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+It's similar to a map to express the whole as you fill it one by one. The jpg picture file we use is a typical bitmap image.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+Vector images, on the other hand, express and save pictures with a mathematical coordinate system at the reference point. So no matter how big I zoom in, I can't break my image.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+It is commonly used when working with images professionally and is often saved in ai file format, which is made by illustrator programs.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+It is expressed as a bitmap image and vector image. If you zoom in on it, Rodi's face appears to be broken.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+Highlights
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+The tutorial will highlight interesting and practical parts that make the word2vec model in TensorFlow.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+Start with motivating why words should be expressed as vectors.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+Explore intuitive beyond the model and how it is learned (along with the use of mathematics for accurate measurement).
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+There is also a simple implementation of the model in TensorFlow.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+Finally, look at ways to make early version levels better.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+Later, the tutorial will show you the code, but if you want to learn more, see Minimalized Implementation.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+This basic example is the code required to download specific data, a code to learn a little
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+It also includes code to visualize the results. As you get used to reading and running the basic version,
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+How to use threads to efficiently move data to a text model
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+You can start an advanced implementation that shows more advanced TensorFlow principles, such as how to check during learning.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+But first, let's look at why we have to learn word embeddedings in the first half.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)+If you are familiar with Embedded and find the details confusing, you can go beyond this.
LOGICAL[(expressed as cross)point position]={Color in field+Cell space in field+Cell Sharing in Field+Angle of cell in field+Automatic cell movement in field+Direction of the cell in the field+Cell Extension in Field+Direction of cell BRIGHTNESS in field)=({(INCLUDE SCREEN BOX TYPE DICTIONARY DEMENTION EXTENCE WINNER POINT POSITION EXPRESS EXPIERENCE[{ALL KIND}POINT POSITION CELL:XELL]ALL KIND DEFENCE)})

Historical usage[edit]+By Aristotle[edit]+Aristotelian logic identifies a proposition as a sentence which affirms or denies a predicate of a subject with the help of a 'Copula'. An Aristotelian proposition may take the form "All men are mortal" or "Socrates is a man." In the first example the subject is "men", predicate is "mortal" and copula is "are". In the second example the subject is "Socrates", the predicate is "a man" and copula is "is".[citation needed]
By the logical positivists[edit]+Often propositions are release{logical({[(selfcom parser[{phasis+phenomology}:Philosophical])logic]logical add kind]:(selfcom meth{Philosophical}kind)}):perpose index write order neested need mean[Philosophical logic
Philosophical logic refers to those areas of philosophy in which recognized methods of logic have traditionally been used to solve or advance the discussion of philosophical problems.[1] Among these, Sybil Wolfram highlights the study of argument, meaning, and truth,[2] while Colin McGinn presents identity, existence, predication, necessity and truth as the main topics of his book on the subject.[3]
Philosophical logic also addresses extensions and alternatives to traditional, "classical" logic known as "non-classical" logics. These receive more attention in texts such as John P. Burgess's Philosophical Logic,[4] the Blackwell Companion to Philosophical Logic,[5] or the multi-volume Handbook of Philosophical Logic[6] edited by Dov M. Gabbay and Franz Guenthner.
]} to closed sentences to distinguish them from what is expressed by an open sentence. In this sense, propositions are "statements" that are truth-bearers. This conception of a proposition was supported by the philosophical school of logical positivism.
Some philosophers argue that some (or all) kinds of speech or actions besides the declarative ones also have propositional content. For example, yes–no questions present propositions, being inquiries into the truth value of them. On the other hand, some signs can be declarative assertions of propositions without forming a sentence nor even being linguistic, e.g. traffic signs convey definite meaning which is either true or false.
Propositions are also spoken of as the content of beliefs and similar intentional attitudes such as desires, preferences, and hopes. For example, "I desire that I have a new car," or "I wonder whether it will snow" (or, whether it is the case that "it will snow"). Desire, belief, and so on, are thus called propositional attitudes when they take this sort of content.[citation needed]
By Russell[edit]+Bertrand Russell held that propositions were structured entities with objects and properties as constituents. One important difference between Ludwig Wittgenstein's view (according to which a proposition is the set of possible worlds/states of affairs in which it is true) is that on the Russellian account, two propositions that are true in all the same states of affairs can still be differentiated. For instance, the proposition that two plus two equals four is distinct on a Russellian account from three plus three equals six. If propositions are sets of possible worlds, however, then all mathematical truths (and all other necessary truths) are the same set (the set of all possible worlds).[citation needed]
Relation to the mind[edit]+In relation to the mind, propositions are discussed primarily as they fit into propositional attitudes. Propositional attitudes are simply attitudes characteristic of folk psychology (belief, desire, etc.) that one can take toward a proposition (e.g. 'it is raining,' 'snow is white,' etc.). In English, propositions usually follow folk psychological attitudes by a "that clause" (e.g. "Jane believes that it is raining"). In philosophy of mind and psychology, mental states are often taken to primarily consist in propositional attitudes. The propositions are usually said to be the "mental content" of the attitude. For example, if Jane has a mental state of believing that it is raining, her mental content is the proposition 'it is raining.' Furthermore, since such mental states are about something (namely propositions), they are said to be intentional mental states. Philosophical debates surrounding propositions as they relate to propositional attitudes have also recently centered on whether they are internal or external to the agent or whether they are mind-dependent or mind-independent entities (see the entry on internalism and externalism in philosophy of mind).
Treatment in logic[edit]+As noted above, in Aristotelian logic a proposition is a particular kind of sentence, one which affirms or denies a predicate of a subject with the help of a copula. Aristotelian propositions take forms like "All men are mortal" and "Socrates is a man."
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+Propositions show up in modern formal logic as objects of a formal language. A formal language begins with different types of symbols. These types can include variables, operators, function symbols, predicate (or relation) symbols, quantifiers, and propositional constants. (Grouping symbols are often added for convenience in using the language but do not play a logical role.) Symbols are concatenated together according to recursive rules in order to construct strings to which truth-values will be assigned. The rules specify how the operators, function and predicate symbols, and quantifiers are to be concatenated with other strings. A proposition is then a string with a specific form. The form that a proposition takes depends on the type of logic.
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+The type of logic called propositional, sentential, or statement logic includes only operators and propositional constants as symbols in its language.
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+The propositions in this language are propositional constants, which are considered atomic propositions, and composite propositions, which are composed by recursively applying operators to propositions. Application here is simply a short way of saying that the corresponding concatenation rule has been applied.
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+The types of logics called predicate, quantificational, or n-order logic include variables, operators, predicate and function symbols, and quantifiers as symbols in their languages. The propositions in these logics are more complex. First, terms must be defined. A term is (i) a variable or (ii) a function symbol applied to the number of terms required by the function symbol's arity. For example, if + is a binary function symbol and x, y, and z are variables, then x+(y+z) is a term, which might be written with the symbols in various orders. A proposition is (i) a predicate symbol applied to the number of terms required by its arity, (ii) an operator applied to the number of propositions required by its arity, or (iii) a logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+quantifier applied to a proposition. For example, if = is a binary predicate symbol and ∀ is a quantifier, then ∀x,y,z [(x = y) → (x+z = y+z)] is a proposition. This more complex structure of propositions allows these logics to make finer distinctions between inferences, i.e., to have greater elogical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+expressive power. +In this context, propositions are also called sentences, statements, statement forms, formulas, and well-formed formulas
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+though these terms are usually not synonymous within a single text. This definition treats propositions as syntactic objects, as opposed to semantic or mental objects. That is, propositions in this sense are meaningless, formal, abstract objects. They are assigned meaning and truth-values by logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+mappings called interpretations and valuations, respectively.
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+Propositions are (browser[{config tele:tell}phone]={[coll:called[structured propositions{selfcom parser add kind{[Logic link{to browser butten demention extence sentence gramma seed need neestedorder mean rectangle(box type area air write[auto voicekeyset])~from boot or adapt connect config advence direct or dynamic device drive all kind{order tree[(box type name{free tree})+{box type include screen mode zoom size write}]}:inter connect config selfcom parser
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+This article is about the systematic study of the form of arguments. For other uses, see Logic (disambiguation).
logical(include meth selfcom only free tree none include write or patch)=only judgment Proposition[(browser[{config tele:tell}phone]={[coll:called[structured propositions{selfcom parser add kind{[Logic link{to browser butten demention extence sentence gramma seed need neestedorder mean rectangle(box type area air write[auto voicekeyset])~from boot or adapt connect config advence direct or dynamic device drive all kind{order tree[(box type name{free tree})+{box type include screen mode zoom size write}]}:inter connect config selfcom parser]+([Part of a series on Philosophy]tree free)
logical(include meth selfcom only free tree none include write or patch)=only judgment Proposition[(browser[{config tele:tell}phone]={[coll:called[structured propositions{selfcom parser add kind{[Logic link{to browser butten demention extence sentence gramma seed need neestedorder mean rectangle(box type area air write[auto voicekeyset])~from boot or adapt connect config advence direct or dynamic device drive all kind{order tree[(box type name{free tree})+{box type include screen mode zoom size write}]}:inter connect config selfcom parser]+([Part of a series on Philosophy]tree free)=[move change limit(cpu main curcle process processign propan kind)=[atteck:defece rotation clock Left to right])]: Plato, Kant, Nietzsche, Buddha, Confucius, Averroes
logical(include meth selfcom only free tree none include write or patch)=only judgment Proposition[(browser[{config tele:tell}phone]={[coll:called[structured propositions{selfcom parser add kind{[Logic link{to browser butten demention extence sentence gramma seed need neestedorder mean rectangle(box type area air write[auto voicekeyset])~from boot or adapt connect config advence direct or dynamic device drive all kind{order tree[(box type name{free tree})+{box type include screen mode zoom size write}]}:inter connect config selfcom parser]+([Part of a series on Philosophy]tree free)=[move change limit(cpu main curcle process processign propan kind)=[atteck:defece rotation clock Left to right])]+[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+Nietzsche
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+Buddha ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+Confucius ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+Averroes
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]=({Philosopher}add kind)meth
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])+Epistemologist
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])+Epistemologist + Ethicists ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])+Epistemologist + Logicians ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])+Epistemologist + Metaphysicians ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])+Epistemologist + Social and political philosophers
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+African ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+ Analytic ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+ Aristotelian ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+ Buddhist ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+ Chinese ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+ Christian ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+ Continental ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+ Existentialism ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+ Hindu ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+ Jain ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+ Jewish ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+ Pragmatism ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+ Eastern ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+ Islamic ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+ Platonic ·
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+ Western
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+(Period point position selfcom parser)
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+(Period point position selfcom parser)+Index
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+(Period point position selfcom parser)+brige([(inside<=>Outside)+{jumpside<=>crosside}+{jumpcrosside<=>crossjumpside}])
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+(Period point position selfcom parser)+brige([(inside<=>Outside)+{jumpside<=>crosside}+{jumpcrosside<=>crossjumpside}]) +move runtime Years
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+(Period point position selfcom parser)+brige([(inside<=>Outside)+{jumpside<=>crosside}+{jumpcrosside<=>crossjumpside}]) +move runtime Years +complex Problems
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+(Period point position selfcom parser)+brige([(inside<=>Outside)+{jumpside<=>crosside}+{jumpcrosside<=>crossjumpside}]) +move runtime Years +complex Problems=([{Publication connect config browser domain host router tcp/ip}address assign]:anwser{lisence})
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+(Period point position selfcom parser)+brige([(inside<=>Outside)+{jumpside<=>crosside}+{jumpcrosside<=>crossjumpside}]) +move runtime Years +complex Problems=([{Publication connect config browser domain host router tcp/ip}address assign]:([anwser{lisence})loop message])=({admin[need Theorie]}add kind)
logical[selfcom only parser(Plato or Kant or Nietzsche) or (Buddha or Confucius or Averroes)]=(selfcom parser add kind meth[Aesthetician])=[acquier add kind(Epistemologist+Ethicists+Logicians+ Metaphysicians+ Metaphysicians)]={[({Philosopher}add kind)meth=Tradition]none move change oma<=>tran}+(Period point position selfcom parser)+brige([(inside<=>Outside)+{jumpside<=>crosside}+{jumpcrosside<=>crossjumpside}]) +move runtime Years +complex Problems=([{Publication connect config browser domain host router tcp/ip}address assign]:([anwser{lisence})loop message])=({admin[need Theorie]}add kind)={[Gloty grass] or [dark grass]}
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]]):{[logical(selfcom parser)=[add kind{concept of a confrontation between beauty and beauty in aesthetic terms}]
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logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[and thus has been ostracized as undermining the pure present in ideology]
logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[However, in modern times, as shown in the literature and art of Baroque]
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logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[research has been underway to find the aesthetic significance of autumn]
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logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[Chasler called the pursuit of material a necessary instrument to recognize]
logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[realize itself through it, and Rosenkrantz, who emphasized]
logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[the aesthetics of the pendulum', has a negative connotation]
logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[LipsT. In Lipps' aesthetics]
logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[it's the subject of direct empathy, but the role of beauty to make it stand out more most]
logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[not to mention the kind of thing that makes it more impressive]
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logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[detestable 3 again. This implies that certain kinds of sublime include an element of ugliness in its form]
logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[spleen often accompanies an expression of disgust]
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logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[in which the pendulum is believed to be a stimulus to invigorate aesthetic impressions and enhance the overall vitality]
logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[when it comes to certain artistic trends, there are a number of works that can bring about a certain aesthetic fascination and impress us]
logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]={In particular, modern existential literature and other arts show what is called ugly beauty}
logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[From pendulum itself is no better than one of the aesthetic categories]
logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[The trend in this sense is to include the elements of discomfort and dissonance as far as possible in the framework of the aesthetic category]
logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[in the opposite position as to the beauty of the agreement or purity]
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logical(selfcom parser)=[([In a narrow senser])meaning that the expression of art destroys aesthetic forms]=[but the significance of this problem in aesthetic categorization should not be ignored]
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.]}+Factory automatically understood the meaning of the text and figure numbers being shaped and made other files play.+Factorys are also rearchitected and link the automation of other scarce orders.+Each uses materials used as an order.
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logical(Movement is expressed as an obituary.+Obital did the math of the element's movements.+It is consistent with the point of security.
But security is a function of avoidance, of approach, of defense.+Each is represented.+It is also happening at the same time)
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may imply otherwise+Another connotation is the other meaning of an order.+It also became the movement of the overlapping meaning of the order.+selfcom parser(Shape the beauty of different characters Did.+The other letters are unique to each country.+Characteristics and Culture = Refreshing the Environment+He also did it.+And selfcom more only makes and does things automatically)
logical(Neisseria gonorrhoeae)+(Neisseria gonorrhoeae)=(browser country{kind:korea}+[domain{(keremargency{hooker})]+config make made[{(config[oecd]:{oced):part:port]}])=[router{tcp/ip}]=(address assign:assign)
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logical{cpu main process processing:procesign config[(to[set or get]syntax)~{from anwser[Reflection of light and shadows mean characters.
Character links appearance with reflection of light.+the calculates the area where the light is reflected on the board.+he redraw his bill and signed off.]}):{[]}]}
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The beauty of the outside is important, but the beauty of the inner More important. That's how you grow your wisdom.You can get peace of mind.}]}
logical{[bravado and hyperbole+a paving expression+{backfeed(stamped into[metaphysics]<[Animation])]}={exneed:[comparison, compare, make a comparison (between), measure A against B
비유[比喩·譬喩]1.figure of speech, compare (A to B), (formal) liken (A to B)
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유사[類似]1.(서로 비슷함) similar, alike (※명사 앞에서는 쓰이지 않음) (상황이) (formal) analogous (to/with)
유사[有史]1.(역사가 시작됨)

주요 어휘comparison[kəmˈpærɪsn]1.(~와) 비교함
2.(A와 B의) 비교, (A를 B에) 비유
contrast1.(둘 이상의 사람사물을 비교했을 때 나타나는 뚜렷한) 차이; 대조, 대비
2.대조적인 사람
3.대조하다, 대비시키다
4.(뚜렷한) 대조를 보이다
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2.(둘 이상의 일이) 아주 유사한
3.…와 아주 유사한 사람
4.유사점
compare(comparison)[-ˈper]1.(A와 B를) 비교하다
2.(~에) 필적하다
with-[wið,wiθ]1. 「뒤쪽으로; 떨어져; 반대로」의 뜻
Size and Height
the symbolism of a picture
Character characteristics
The shape or flower of a character's face.
The words of a flower represent the lettering of a symbol.
]}



exneed:Gonococcal urethritis PHIL 4085 lores.jpg
Gram-stain of gonococcal urethritis. Note distribution in neutrophils and presence of both intracellular and extracellular bacteria. (CDC)

Scientific classification

Domain: Bacteria
Phylum: Proteobacteria
Class: Betaproteobacteria
Order: Neisseriales
Family: Neisseriaceae
Genus: Neisseria
Species: N. gonorrhoeae
Binomial name
Neisseria gonorrhoeae
(Zopf 1885) Trevisan 1885[1]
Synonyms
Micrococcus der Gonorrhoe Neisser 1879[2]
Gonococcus neisseri Lindau 1898
Neisseria gonorrhoeae, also known as gonococcus (singular), or gonococci (plural) is a species of Gram-negative diplococci bacteria isolated by Albert Neisser in 1879.[3] It causes the sexually transmitted genitourinary infection gonorrhea[4] as well as other forms of gonococcal disease including disseminated gonococcemia, septic arthritis, and gonococcal ophthalmia neonatorum.
It is oxidase positive and aerobic, and it survives within neutrophils.[4] Culturing it requires carbon dioxide supplementation and enriched agar (chocolate agar) with various antimicrobials (Thayer-Martin). It exhibits antigenic variation through recombination of its pili and surface proteins that interact with the immune system.[3]
Sexual transmission is possible through vaginal, anal, or oral sex.[5] Sexual transmission may be prevented through the use of barrier protection.[6] Perinatal transmission may occur during childbirth, and may be prevented by antibiotic treatment of the mother before birth and the application of antibiotic eye gel on the eyes of the newborn.[6] After an episode of gonococcal infection, infected persons do not develop immunity to future infections. Reinfection is possible due to N. gonorrhoeae's ability to evade the immune system by varying its surface proteins.[7]
N. gonorrhoeae can cause infection of the genitals, throat, and eyes.[7] Asymptomatic infection is common in males and females.[8][6][9] Untreated infection may spread to the rest of the body (disseminated gonorrhea infection), especially the joints (septic arthritis). Untreated infection in women may cause pelvic inflammatory disease and possible infertility due to the resulting scarring.[7] Diagnosis is through culture, Gram stain, or polymerase chain reaction testing of a urine sample, urethral swab, or cervical swab.[10][11] Chlamydia co-testing and testing for other STI's is recommended due to high rates of coinfection.[10]
Contents [hide]
1 Microbiology 1.1 Culture and identification
1.2 Surface proteins
1.3 Antigenic variation
1.4 Survival of gonococci
2 Genome 2.1 Horizontal gene transfer
3 Disease 3.1 Transmission
3.2 Prevention
3.3 Treatment 3.3.1 Antibiotic resistance
4 History 4.1 Name origin
4.2 Discovery
5 See also
6 References
7 External links
Microbiology[edit]
Neisseria species are fastidious, Gram-negative cocci that require nutrient supplementation to grow in laboratory cultures. Neisseria spp. are facultatively intracellular and typically appear in pairs (diplococci), resembling the shape of coffee beans. Nesseria is nonspore-forming, nonmotile, and an obligate aerobe (requires oxygen to grow). Of the 11 species of Neisseria that colonize humans, only two are pathogens. N. gonorrhoeae is the causative agent of gonorrhea (also called "the clap") and N. meningitidis is one cause of bacterial meningitis.
Culture and identification[edit]
Thayer-Martin agar is selective for growth of Neisseria species. Further testing (oxidase, Gram stain, carbohydrate use) is needed to differentiate N. gonorrhoeae from N. meningitidis
Carbohydrate utilization of Neisseria gonorrhoeae: N. gonorrhoeae will oxidise glucose, not maltose, sucrose, or lactose; N. meningitidis ferments glucose and maltose.
N. gonorrhoeae is usually isolated on Thayer-Martin agar (or VPN) agar in an environment enriched with 3-7% carbon dioxide.[10] Thayer-Martin agar is a chocolate agar plate (heated blood agar) containing nutrients and antimicrobials (vancomycin, colistin, nystatin, and trimethoprim). This agar preparation facilitates the growth of Neisseria species while inhibiting the growth of contaminating bacteria and fungi. Martin Lewis and New York City agar are other types of selective chocolate agar commonly used for Neisseria growth.[10] N. gonorrhoeae is oxidase positive (possessing cytochrome c oxidase) and catalase positive (able to convert hydrogen peroxide to oxygen).[10] When incubated with the carbohydrates lactose, maltose, sucrose, and glucose, N. gonorrhoeae will oxidize only the glucose.[10]
Surface proteins[edit]
On its surface, N. gonorrhoeae bears hair-like pili, surface proteins with various functions, and sugars called lipooligosaccharides. The pili mediate adherence, movement, and DNA exchange. The Opa proteins interact with the immune system, as do the porins. Lipooligosaccharide (LPS) is an endotoxin that provokes an immune response. All are antigenic and all exhibit antigenic variation (see below). The pili exhibit the most variation. The pili, Opa proteins, porins, and even the LOS have mechanisms to inhibit the immune response, making asymptomatic infection possible.[12]

Dynamic polymeric protein filaments called type IV pili allow N. gonorrhoeae to adhere to and move along surfaces. To enter the host the bacteria uses the pili to adhere to and penetrate mucosal surfaces.[4] The pili are a necessary virulence factor for N. gonorrhoeae; without them, the bacterium is unable to cause infection.[7] To move, the bacterium uses the type IV pili like a grappling hook, extending and retracting it for movement. Pili extend and attach to a substrate that signals the pilus to retract, dragging the cell forward. The resulting movement is referred to as twitching motility.[13] N. gonorrhoeae is able to pull 100,000 times its own weight, and it has been claimed that the pili used to do so are the strongest biological motor known to date, exerting one nanonewton.[14] A set of ATPase proteins power the pulling actions of the type IV pilus: Pil F (extension) and Pil T (retraction).[15][16] The adhesive functions of the gonococcal pilus play a role in microcolony aggregation and biofilm formation.
This illustration depicts a Gram stain of a urethral exudate showing typical intracellular Gram-negative diplococci, and pleomorphic extracellular Gram-negative organisms, which is diagnostic for gonococcal urethritis.
Surface proteins called Opa proteins can be used to bind to receptors on immune cells and prevent an immune response. At least 12 Opa proteins are known and the many permutations of surface proteins make recognizing N. gonorrhoeae and mounting a defense by immune cells more difficult.[17]

Lipooligosaccharide (LOS) is a low-weight version of lipopolysaccharide present on the surfaces of most other Gram-negative bacteria. It is a sugar (saccharide) side chain attached to lipid A (thus "lipo-") in the outer membrane coating the cell wall of the bacteria. The root "oligo" refers to the fact that it is a few sugars shorter than the typical lipopolysaccharide.[4] As an endotoxin, LOS provokes inflammation. The shedding of LOS by the bacteria is responsible for local injury in, for example, pelvic inflammatory disease.[4] Although its main function is as an endotoxin, LOS may disguise itself with host sialic acid and block initiation of the complement cascade.[4]

Antigenic variation[edit]

N. gonorrhoeae evades the immune system through a process called antigenic variation, in which the N. gonorrhoeae bacterium is able to recombine its genes and alter the antigenic determinants (sites where antibodies bind) such as the Opa proteins[18] and Type IV pili[19] that adorn its surface.[4] It is able to vary the composition of its pili, Opa proteins, and LOSs; of these, the pili exhibit the most antigenic variation due to chromosomal rearrangement.[7][4] Every time the bacteria replicate, they may switch multiple Opa proteins on or off through slipped-strand mispairing. That is, the bacteria introduce frameshift mutations that bring genes in or out of frame. The result is that different Opa genes are translated every time.[4] In addition to the ability to rearrange the genes it already has, it is also naturally competent to acquire new DNA, via its type IV pilus, specifically proteins Pil Q and Pil T.[20] These processes allow N. gonorrhoeae to acquire/spread new genes, disguise itself with different surface proteins, and prevent the development of immunological memory – an ability which has led to antibiotic resistance and has made vaccine development difficult.[21]

Survival of gonococci[edit]

After gonococci invade and transcytose the host epithelial cells, they land in the submucosa, where neutrophils promptly consume them.[4] The pili and Opa proteins on the surface may interfere with phagocytosis,[7] but most gonococci end up in neutrophils. The exudates from infected individuals contain many neutrophils with ingested gonococci. Neutrophils release an oxidative burst of reactive oxygen species in their phagosomes to kill the gonococci.[22] However, a significant fraction of the gonococci can resist killing through the action of their catalase[4] which breaks down reactive oxygen species and is able to reproduce within the neutrophil phagosomes.

Stohl and Seifert showed that the bacterial RecA protein, which mediates repair of DNA damage, plays an important role in gonococcal survival.[23] Michod et al. have suggested that N. gonorrhoeae may replace DNA damaged in neutrophil phagosomes with DNA from neighboring gonococci.[24] The process in which recipient gonococci integrate DNA from neighboring gonococci into their genome is called transformation.
The growth of N. gonorrhoeae colonies on New York City agar, a specialized and selective medium for gonococci
Genome[edit]

The genomes of several strains of N. gonorrhoeae have been sequenced. Most of them are about 2.1 Mb in size and encode 2,100 to 2,600 proteins (although most seem to be in the lower range).[25] For instance, strain NCCP11945 consists of one circular chromosome (2,232,025 bp) encoding 2,662 predicted open reading frames (ORFs) and one plasmid (4,153 bp) encoding 12 predicted ORFs. The estimated coding density over the entire genome is 87%, and the average G+C content is 52.4%, values that are similar to those of strain FA1090. The NCCP11945 genome encodes 54 tRNAs and four copies of 16S-23S-5S rRNA operons.[26]

Horizontal gene transfer[edit]

In 2011, researchers at Northwestern University found evidence of a human DNA fragment in a N. gonorrhoeae genome, the first example of horizontal gene transfer from humans to a bacterial pathogen

Disease[edit]

Main article: Gonorrhoea

Symptoms of infection with N. gonorrhoeae differ, depending on the site of infection. Also, many infected men are asymptomatic and most infected females (50-80%) are asymptomatic

In symptomatic men, the primary symptom of genitourinary infection is urethritis – burning with urination (dysuria), increased urge to urinate, and a pus-like (purulent) discharge from the penis. The discharge may be foul smelling.[4] If untreated, scarring of the urethra may result in difficulty urinating. Infection may spread from the urethra in the penis to nearby structures, including the testicles (epididymitis/orchitis), or to the prostate (prostatitis) Men who have had a gonorrhea infection have a significantly increased risk of having prostate cancer.[30]

In symptomatic women, the primary symptoms of genitourinary infection are increased vaginal discharge, burning with urination (dysuria), increased urge to urinate, pain with intercourse, or menstrual abnormalities. Pelvic inflammatory disease results if N. gonorrhoeae ascends into the pelvic peritoneum (via the cervix, endometrium, and fallopian tubes). The resulting inflammation and scarring of the fallopian tubes can lead to infertility and increased risk of ectopic pregnancy.[4] Pelvic inflammatory disease develops in 10 to 20% of the females infected with N. gonorrhoeae.

N. gonorrhoeae may cause infection of the throat (pharyngitis) through oral sex. Infected persons may experience sore throat and swollen lymph nodes, or may be asymptomatic.
N. gonorrhoeae may cause infection of the anus/rectum (proctitis) through anal sex. Infected persons may experience blood or a pus-like discharge, or may be asymptomatic.
In perinatal infection, the primary manifestation is infection of the eye (neonatal conjunctivitis or ophthalmia neonatorum) when the newborn is exposed to N. gonorrhoeae in the birth canal. The eye infection can lead to corneal scarring or perforation, ultimately resulting in blindness. If the newborn is exposed during birth, conjunctivitis occurs within 2–5 days after birth and is severe. Gonococcal ophthalmia neonatorum, once common in newborns, is prevented by the application of erythromycin (antibiotic) gel to the eyes of babies at birth as a public health measure. Silver nitrate is no longer used in the United States.[31][4]
Disseminated N. gonorrhoeae infections can occur in which gonococci enter the bloodstream, often spreading to the joints and causing a rash (dermatitis-arthritis syndrome).Dermatitis-arthritis syndrome presents with joint pain (arthritis), tendon inflammation (tenosynovitis), and painless non-pruritic (non-itchy) dermatitis. Disseminated infection and PID tend to begin after menses due to reflux during menses, facilitating spread. Rarely, disseminated infection may cause infection of the meninges of the brain and spinal cord (meningitis) or infection of the heart valves (endocarditis).
Transmission[edit]
N. gonorrhoeae may be transmitted through vaginal, oral, or anal sex; nonsexual transmission is unlikely in adult infection.[5] It can also be transmitted to the newborn during passage through the birth canal if the mother has untreated genitourinary infection. Given the high rate of asymptomatic infection, all pregnant women should be tested for gonorrhea infection.[5]
Traditionally, the bacterium was thought to move attached to spermatozoa, but this hypothesis did not explain female to male transmission of the disease. A recent study suggests that rather than "surf" on wiggling sperm, N. gonorrhoeae bacteria use pili to anchor onto proteins in the sperm and move through coital liquid.[32]
Prevention[edit]
Transmission can be reduced by using latex barriers (e.g. condoms or dental dams) during sex and by limiting sexual partners.[6] Condoms and dental dams should be used during oral and anal sex, as well. Spermicides, vaginal foams, and douches are not effective for prevention of transmission.[4]
Treatment[edit]
Ceftriaxone (a third-generation cephalosporin) is the first line treatment.[33] Because co-infection with chlamydia is so common, people are often treated for both by combining ceftriaxone with azithromycin or doxycycline.[4] Azithromycin is preferred for additional coverage of gonorrhea that may be resistant to cephalosporins but susceptible to macrolides.[34][6] Sexual partners (defined by the CDC as sexual contact within the past 60 days)[11] should also be notified, tested, and treated.[6][33]
Antibiotic resistance[edit]
Antibiotic resistance in gonorrhea has been noted beginning in the 1940s. Gonorrhea was treated with penicillin, but doses had to be progressively increased to remain effective. By the 1970s, penicillin- and tetracycline-resistant gonorrhea emerged in the Pacific Basin. These resistant strains then spread to Hawaii, California, the rest of the United States, and Europe. Fluoroquinolones were the next line of defense, but soon resistance to this antibiotic emerged, as well. Since 2007, standard treatment has been third-generation cephalosporins, such as ceftriaxone, which are considered to be our "last line of defense".[35][36]
Recently, a high-level ceftriaxone-resistant strain of gonorrhea called H041 was discovered in Japan. Lab tests found it to be resistant to high concentrations of ceftriaxone, as well as most of the other antibiotics tested. Within N. gonorrhoeae, genes exist that confer resistance to every single antibiotic used to cure gonorrhea, but thus far they do not coexist within a single gonococcus. However, because of N. gonorrhoeae's high affinity for horizontal gene transfer, antibiotic-resistant gonorrhea is seen as an emerging public health threat.
Neisseria gonnorhoeae is named for Albert Neisser, who isolated it as the causative agent of the disease gonorrhea incoined the term "gonorrhea" from the Greek gonos which means "seed" and rhoe which means "flow". Thus, gonorrhea means "flow of seed", a description referring to the white penile discharge, assumed to be semen, seen in male infection.


In 1878, Albert Neisser isolated and visualized N. gonorrhoeae diplococci in samples of pus from 35 men and women with the classic symptoms of genitourinary infection with gonorrhea – two of whom also had infections of the eyes.[40] In 1882, Leistikow and Loeffler were able to grow the organism in culture.[37] Then in 1883, Max Bockhart proved conclusively that the bacterium isolated by Albert Neisser was the causative agent of the disease known as gonorrhea by inoculating the penis of a healthy man with the bacteria.[40] The man developed the classic symptoms of gonorrhea days after, satisfying the last of Koch's postulates. Until this point, researchers debated whether syphilis and gonorrhea were manifestations of the same disease or two distinct entities.[41][40][39] One such 18th-century researcher, John Hunter, tried to settle the debate in 1767[39] by inoculating a man with pus taken from a patient with gonorrhea. He erroneously concluded that both syphilis and gonorrhea were indeed the same disease when the man developed the copper-colored rash that is classic for syphilis.[42][41] Although many sources repeat that Hunter inoculated himself,[42][37] others have argued that it was in fact another man.[43] After Hunter's experiment other scientists sought to disprove his conclusions by inoculating other male physicians, medical students,[37] and incarcerated men with gonorrheal pus, who all developed the burning and discharge of gonorrhea. One researcher, Ricord, took the initiative to perform 667 inoculations of gonorrheal pus on patients of a mental hospital, with zero cases of syphilis.[39][37] Notably, the advent of penicillin in the 1940s made effective treatments for gonorrhea available.

2018년 10월 14일 (일) 22:02 판