악티노닌

악티노닌
이름
	우선명 (PIN) (2R)-N4-Hydroxy-N1-{(2S)-1-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl}-2-pentylbutanediamide
식별자
CAS 번호	13434-13-4 ;
3D 모델 (JSmol)	Interactive image;
ChEMBL	ChEMBL308333 ;
ChemSpider	391756 ;
DrugBank	DB04310 ;
PubChem CID	443600;
UNII	P18SPA8N0K ;
CompTox Dashboard (EPA)	DTXSID70928580 ;
	InChI InChI=1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)/t14-,15+,17+/m1/s1 Key: XJLATMLVMSFZBN-VYDXJSESSA-N ; InChI=1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24)/t14-,15+,17+/m1/s1;
	SMILES O=C(N1[C@H](CO)CCC1)[C@@H](NC(=O)[C@H](CCCCC)CC(=O)NO)C(C)C;
성질
화학식	C19H35N3O5
몰 질량	385.505 g·mol−1
	달리 명시된 경우를 제외하면, 표준상태(25 °C [77 °F], 100 kPa)에서 물질의 정보가 제공됨. 확인 (관련 정보 ?) 정보상자 각주

악티노닌(영어: actinonin)은 항종양 활성이 입증된 자연에서 생성되는 항균제이다.^[1] 악티노닌은 세균에 필수적인 효소인 펩타이드 탈폼일화효소를 저해하는 것으로 나타났다.^[2]

같이 보기[편집]

↑ Chen, D.Z.; Patel, D.V. (2000). “Actinonin, a Naturally Occurring Antibacterial Agent, Is a Potent Deformylase Inhibitor”. 《Biochemistry》 39 (6): 1256–62. doi:10.1021/bi992245y. PMID 10684604.
↑ Yoon, Hye-Jin; Kim, Hye Lee; Lee, Soo-Kyoung; Kim, Hyun-Woo; Kim, Hyung-Wook; Lee, Jae Young; Mikami, Bunzo; Suh, Se Won (2004). “Crystal structure of peptide deformylase from Staphylococcus aureus in complex with actinonin, a naturally occurring antibacterial agent”. 《Proteins: Structure, Function, and Bioinformatics》 (영어) 57 (3): 639–642. doi:10.1002/prot.20231. ISSN 1097-0134. PMID 15382235. S2CID 42929776.