리시닌

리시닌
이름
	IUPAC 이름 4-Methoxy-1-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
	별칭 3-cyano-4-methoxy-N-methyl-2-pyridone
식별자
CAS 번호	524-40-3;
3D 모델 (JSmol)	Interactive image;
3DMet	B00311;
ChEBI	CHEBI:18043;
ChEMBL	ChEMBL1329957;
ChemSpider	10216;
ECHA InfoCard	100.007.601
EC 번호	208-359-7;
KEGG	C01526;
PubChem CID	10666;
UNII	130UFS7AE0;
CompTox Dashboard (EPA)	DTXSID50200412 ;
	InChI InChI=1S/C8H8N2O2/c1-10-4-3-7(12-2)6(5-9)8(10)11/h3-4H,1-2H3 Key: PETSAYFQSGAEQY-UHFFFAOYSA-N;
	SMILES Cn1ccc(c(c1=O)C#N)OC;
성질
화학식	C8H8N2O2
몰 질량	164.164 g·mol−1
녹는점	200 °C (392 °F; 473 K)
위험
	반수 치사량 또는 반수 치사농도 (LD, LC):
LD50 (median dose)	340 mg/kg
	달리 명시된 경우를 제외하면, 표준상태(25 °C [77 °F], 100 kPa)에서 물질의 정보가 제공됨. 정보상자 각주

리시닌(Ricinine)은 피마자에서 발견되는 독성 알칼로이드이다.^[2] 리친 독성의 생물지표 역할을 할 수 있다.^[3]^[4]

리시닌은 살충 효과가 있다.^[5]

같이 보기

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리시닌

리친

각주

↑ Worbs, Sylvia; Köhler, Kernt; Pauly, Diana; Avondet, Marc-André; Schaer, Martin; Dorner, Martin B.; Dorner, Brigitte G. (2011년 10월 24일). “Ricinus communis Intoxications in Human and Veterinary Medicine—A Summary of Real Cases”. 《Toxins》 3 (10): 1332–1372. doi:10.3390/toxins3101332. PMC 3210461. PMID 22069699.
↑ Peng, Jing; Cai, Shuang; Wang, Lin; Zhao, Nan; Zhang, Ting-jian; Chen, Zai-xing; Meng, Fan-hao; Dzeja, Petras (2014년 3월 11일). “A Metabonomic Analysis of Serum from Rats Treated with Ricinine Using Ultra Performance Liquid Chromatography Coupled with Mass Spectrometry”. 《PLoS ONE》 9 (3): e90416. Bibcode:2014PLoSO...990416P. doi:10.1371/journal.pone.0090416. PMC 3949718. PMID 24618672.
↑ Hamelin, Elizabeth I.; Johnson, Rudolph C.; Osterloh, John D.; Howard, David J.; Thomas, Jerry D. (November 2012). “Evaluation of Ricinine, a Ricin Biomarker, from a Non-Lethal Castor Bean Ingestion”. 《Journal of Analytical Toxicology》 36 (9): 660–662. doi:10.1093/jat/bks077. PMC 4561852. PMID 23014889.
↑ Pittman, C. T.; Guido, J. M.; Hamelin, E. I.; Blake, T. A.; Johnson, R. C. (2013년 3월 6일). “Analysis of a Ricin Biomarker, Ricinine, in 989 Individual Human Urine Samples”. 《Journal of Analytical Toxicology》 37 (4): 237–240. doi:10.1093/jat/bkt010. PMC 4547525. PMID 23471955.
↑ Wachira, Sabina; Omar, Sabar; Jacob, Julia; Wahome, Martin; Alborn, Hans T; Spring, David R; Masiga, Daniel K; Torto, Baldwyn (2014). “Toxicity of six plant extracts and two pyridone alkaloids from Ricinus communis against the malaria vector Anopheles gambiae”. 《Parasites & Vectors》 7 (1): 312. doi:10.1186/1756-3305-7-312. PMC 4098926. PMID 24996560.

[1] Worbs, Sylvia; Köhler, Kernt; Pauly, Diana; Avondet, Marc-André; Schaer, Martin; Dorner, Martin B.; Dorner, Brigitte G. (2011년 10월 24일). “Ricinus communis Intoxications in Human and Veterinary Medicine—A Summary of Real Cases”. 《Toxins》 3 (10): 1332–1372. doi:10.3390/toxins3101332. PMC 3210461. PMID 22069699.

[2] Peng, Jing; Cai, Shuang; Wang, Lin; Zhao, Nan; Zhang, Ting-jian; Chen, Zai-xing; Meng, Fan-hao; Dzeja, Petras (2014년 3월 11일). “A Metabonomic Analysis of Serum from Rats Treated with Ricinine Using Ultra Performance Liquid Chromatography Coupled with Mass Spectrometry”. 《PLoS ONE》 9 (3): e90416. Bibcode:2014PLoSO...990416P. doi:10.1371/journal.pone.0090416. PMC 3949718. PMID 24618672.

[3] Hamelin, Elizabeth I.; Johnson, Rudolph C.; Osterloh, John D.; Howard, David J.; Thomas, Jerry D. (November 2012). “Evaluation of Ricinine, a Ricin Biomarker, from a Non-Lethal Castor Bean Ingestion”. 《Journal of Analytical Toxicology》 36 (9): 660–662. doi:10.1093/jat/bks077. PMC 4561852. PMID 23014889.

[4] Pittman, C. T.; Guido, J. M.; Hamelin, E. I.; Blake, T. A.; Johnson, R. C. (2013년 3월 6일). “Analysis of a Ricin Biomarker, Ricinine, in 989 Individual Human Urine Samples”. 《Journal of Analytical Toxicology》 37 (4): 237–240. doi:10.1093/jat/bkt010. PMC 4547525. PMID 23471955.

[5] Wachira, Sabina; Omar, Sabar; Jacob, Julia; Wahome, Martin; Alborn, Hans T; Spring, David R; Masiga, Daniel K; Torto, Baldwyn (2014). “Toxicity of six plant extracts and two pyridone alkaloids from Ricinus communis against the malaria vector Anopheles gambiae”. 《Parasites & Vectors》 7 (1): 312. doi:10.1186/1756-3305-7-312. PMC 4098926. PMID 24996560.

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