DNAJB1

DNAJB1
사용 가능한 구조
PDB	동원체 검색: PDBe RCSB
PDB ID 코드 목록
	1HDJ, 2QLD, 3AGX, 3AGY, 3AGZ, 4WB7
식별자
다른 이름	DNAJB1, HSPF1, Hdj1, Hsp40, RSPH16B, Sis1, DnaJ heat shock protein family (Hsp40) member B1
외부 ID	OMIM: 604572 MGI: 1931874 HomoloGene: 55957 GeneCards: DNAJB1
유전자 위치 (인간)
염색체	19번 염색체
끝	14,560,391 bp
유전자 위치 (쥐)
염색체	8번 염색체 (쥐)
끝	84,339,282 bp
RNA 발현 패턴
	최상위 발현
	쓸개; ; 기관; ; epithelium of esophagus; ; 질; ; cardia; ; oral cavity; ; 대정맥; ; ganglionic eminence; ; body of tongue; ; 배의 피부;
	최상위 발현
	세정관; ; 운동 신경 세포; ; utricle; ; primitive streak; ; 상행대동맥; ; aortic valve; ; fossa; ; conjunctival fornix; ; spermatid; ; condyle;
	추가 참조 발현 데이터
	; ;
	추가 참조 발현 데이터
유전자 온톨로지
분자 함수	unfolded protein binding; ATPase binding; Hsp70 protein binding; chaperone binding; 단백질 결합; ATPase activator activity; transcription corepressor activity; cadherin binding;
세포 성분	세포액; 핵소체; 엑소좀; 세포핵; 핵질; 세포질; postsynaptic density; neuronal cell body; dendritic spine; sperm head; postsynapse; glutamatergic synapse;
생물학적 과정	regulation of cellular response to heat; response to unfolded protein; positive regulation of ATP-dependent activity; 단백질 접힘; chaperone cofactor-dependent protein refolding; negative regulation of inclusion body assembly; negative regulation of transcription from RNA polymerase II promoter in response to stress; negative regulation of transcription by RNA polymerase II; forebrain development;
	출처: Amigo / QuickGO
동원체
	3337
	81489
	ENSG00000132002
	ENSMUSG00000005483
	P25685
	Q9QYJ3
	NM_001313964; NM_001300914; NM_006145
	NM_018808; NM_001308227
	NP_001287843; NP_001300893; NP_006136
	NP_001295156; NP_061278
	위키데이터
인간 보기/편집	쥐 보기/편집

DnaJ 상동체 서브 패밀리 B 구성원 1(DnaJ homolog subfamily B member 1)은 인간에서 DNAJB1 유전자에 의해 암호화되는 단백질이다.^[5]^[6]^[7]

상호작용[편집]

DNAJB1은 HSPA4, STUB1과 상호작용하는 것으로 나타났다.

각주[편집]

↑ ^가 ^나 ^다 GRCh38: Ensembl release 89: ENSG00000132002 - 앙상블, May 2017
↑ ^가 ^나 ^다 GRCm38: Ensembl release 89: ENSMUSG00000005483 - 앙상블, May 2017
↑ “Human PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.
↑ “Mouse PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.
↑ “Genomic cloning of a human heat shock protein 40 (Hsp40) gene (HSPF1) and its chromosomal localization to 19p13.2”. 《Genomics》 38 (3): 446–9. Mar 1997. doi:10.1006/geno.1996.0653. PMID 8975727.
↑ Ohtsuka K (Jan 1994). “Cloning of a cDNA for heat-shock protein hsp40, a human homologue of bacterial DnaJ”. 《Biochem Biophys Res Commun》 197 (1): 235–40. doi:10.1006/bbrc.1993.2466. PMID 8250930.
↑ “Entrez Gene: DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1”.

[refGRCh38Ensembl-1] 가 ^나 ^다 GRCh38: Ensembl release 89: ENSG00000132002 - 앙상블, May 2017

[refGRCm38Ensembl-2] 가 ^나 ^다 GRCm38: Ensembl release 89: ENSMUSG00000005483 - 앙상블, May 2017

[3] “Human PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.

[4] “Mouse PubMed Reference:”. 《National Center for Biotechnology Information, U.S. National Library of Medicine》.

[pmid8975727-5] “Genomic cloning of a human heat shock protein 40 (Hsp40) gene (HSPF1) and its chromosomal localization to 19p13.2”. 《Genomics》 38 (3): 446–9. Mar 1997. doi:10.1006/geno.1996.0653. PMID 8975727.

[pmid8250930-6] Ohtsuka K (Jan 1994). “Cloning of a cDNA for heat-shock protein hsp40, a human homologue of bacterial DnaJ”. 《Biochem Biophys Res Commun》 197 (1): 235–40. doi:10.1006/bbrc.1993.2466. PMID 8250930.

[entrez-7] “Entrez Gene: DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1”.

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