브라운 세카르 증후군

브라운 세카르 증후군
브라운 세카르 증후군
진료과	신경과

브라운 세카르 증후군(Brown-Séquard syndrome, Brown-Séquard's hemiplegia, Brown-Séquard's paralysis, hemiparaplegic syndrome, hemiplegia et hemiparaplegia spinalis, spinal hemiparaplegia)은 척수의 한 면이 손상되어 나타나는 질병으로, 상해나 병변이 있는 동일(동촉)한 면에 고유 수용성 감각의 마비 및 손실을 일으키며 병변의 반대쪽(대측)에 통증과 온도 감각의 손실을 일으킨다. 본 병명은 1850년 이 질병을 처음 기술한 생리학자 찰스 에두아르 브라운 세카르의 이름을 따서 지어졌다.^[1]

진단[편집]

척수병의 경우 자기공명영상(MRI)을 사용하여 진단한다.

병인[편집]

브라운 세카르 증후군은 척수 종양, 정신외상, 허혈, 감염, 염증 질병(결핵 등), 다발성 경화증에 의해 발병할 수 있다. 잠수병 또한 브라운 세커드 증후군의 병인으로 될 수 있다.^[2]

치료[편집]

치료는 마비를 일으키는 병리적 측면에 초점을 둔다. 총상이나 칼로 인한 상해와 같은 정신적 외상으로 인한 것이라면 출혈이나 주요 장기 부상과 같은 생명에 위협을 주는 질병이 더 있을 수 있으므로 응급 조치가 필요할 수 있다. 증후군이 척추 골절로 인한 것이라면 식별 후 적절한 치료를 받아야 한다. 종창과 염증을 완화하는데 스테로이드를 사용할 수 있지만 척추 손상에 대한 치료가 필요할 수 있다.^[3]

각주[편집]

↑ C.-É. Brown-Séquard: De la transmission croisée des impressions sensitives par la moelle épinière. Comptes rendus de la Société de biologie, (1850)1851, 2: 33-44.
↑ Kimbro, T; Tom, T; Neuman, T (May 1997). “A case of spinal cord decompression sickness presenting as partial Brown-Sequard syndrome.”. 《Neurology》 48 (5): 1454–6. doi:10.1212/wnl.48.5.1454. PMID 9153492.
↑
See:
- Egido Herrero JA, Saldanã C, Jiménez A, Vázquez A, Varela de Seijas E, Mata P (1992). “Spontaneous cervical epidural hematoma with Brown-Séquard syndrome and spontaneous resolution. Case report”. 《J Neurosurg Sci》 36 (2): 117–9. PMID 1469473.
- Ellger T, Schul C, Heindel W, Evers S, Ringelstein EB (June 2006). “Idiopathic spinal cord herniation causing progressive Brown-Séquard syndrome”. 《Clin Neurol Neurosurg》 108 (4): 388–91. doi:10.1016/j.clineuro.2004.07.005. PMID 16483712.
- Finelli PF, Leopold N, Tarras S (May 1992). “Brown-Sequard syndrome and herniated cervical disc”. 《Spine》 17 (5): 598–600. doi:10.1097/00007632-199205000-00022. PMID 1621163.
- Hancock JB, Field EM, Gadam R (1997). “Spinal epidural hematoma progressing to Brown-Sequard syndrome: report of a case”. 《J Emerg Med》 15 (3): 309–12. doi:10.1016/S0736-4679(97)00010-3. PMID 9258779.
- Harris P (November 2005). “Stab wound of the back causing an acute subdural haematoma and a Brown-Sequard neurological syndrome”. 《Spinal Cord》 43 (11): 678–9. doi:10.1038/sj.sc.3101765. PMID 15852056.
- Henderson SO, Hoffner RJ (1998). “Brown-Sequard syndrome due to isolated blunt trauma”. 《J Emerg Med》 16 (6): 847–50. doi:10.1016/S0736-4679(98)00096-1. PMID 9848698.
- Hwang W, Ralph J, Marco E, Hemphill JC (June 2003). “Incomplete Brown-Séquard syndrome after methamphetamine injection into the neck”. 《Neurology》 60 (12): 2015–6. doi:10.1212/01.wnl.0000068014.89207.99. PMID 12821761.
- Kraus JA, Stüper BK, Berlit P (1998). “Multiple sclerosis presenting with a Brown-Séquard syndrome”. 《J. Neurol. Sci.》 156 (1): 112–3. doi:10.1016/S0022-510X(98)00016-1. PMID 9559998.
- Lim E, Wong YS, Lo YL, Lim SH (April 2003). “Traumatic atypical Brown-Sequard syndrome: case report and literature review”. 《Clin Neurol Neurosurg》 105 (2): 143–5. doi:10.1016/S0303-8467(03)00009-X. PMID 12691810.
- Lipper MH, Goldstein JH, Do HM (August 1998). “Brown-Séquard syndrome of the cervical spinal cord after chiropractic manipulation”. 《AJNR Am J Neuroradiol》 19 (7): 1349–52. PMID 9726481.
- Mastronardi L, Ruggeri A (January 2004). “Cervical disc herniation producing Brown-Sequard syndrome: case report”. 《Spine》 29 (2): E28–31. doi:10.1097/01.BRS.0000105984.62308.F6. PMID 14722422.
- Miyake S, Tamaki N, Nagashima T, Kurata H, Eguchi T, Kimura H (February 1998). “Idiopathic spinal cord herniation. Report of two cases and review of the literature”. 《J. Neurosurg.》 88 (2): 331–5. doi:10.3171/jns.1998.88.2.0331. PMID 9452246.
- Rumana CS, Baskin DS (April 1996). “Brown-Sequard syndrome produced by cervical disc herniation: case report and literature review”. 《Surg Neurol》 45 (4): 359–61. doi:10.1016/0090-3019(95)00412-2. PMID 8607086.
- Stephen AB, Stevens K, Craigen MA, Kerslake RW (October 1997). “Brown-Séquard syndrome due to traumatic brachial plexus root avulsion”. 《Injury》 28 (8): 557–8. doi:10.1016/S0020-1383(97)83474-2. PMID 9616398.

외부 링크[편집]

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브라운 세카르 증후군

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이 글은 질병에 관한 토막글입니다. 여러분의 지식으로 알차게 문서를 완성해 갑시다.

[1] C.-É. Brown-Séquard: De la transmission croisée des impressions sensitives par la moelle épinière. Comptes rendus de la Société de biologie, (1850)1851, 2: 33-44.

[2] Kimbro, T; Tom, T; Neuman, T (May 1997). “A case of spinal cord decompression sickness presenting as partial Brown-Sequard syndrome.”. 《Neurology》 48 (5): 1454–6. doi:10.1212/wnl.48.5.1454. PMID 9153492.

[3] See:
Egido Herrero JA, Saldanã C, Jiménez A, Vázquez A, Varela de Seijas E, Mata P (1992). “Spontaneous cervical epidural hematoma with Brown-Séquard syndrome and spontaneous resolution. Case report”. 《J Neurosurg Sci》 36 (2): 117–9. PMID 1469473.

Ellger T, Schul C, Heindel W, Evers S, Ringelstein EB (June 2006). “Idiopathic spinal cord herniation causing progressive Brown-Séquard syndrome”. 《Clin Neurol Neurosurg》 108 (4): 388–91. doi:10.1016/j.clineuro.2004.07.005. PMID 16483712.

Finelli PF, Leopold N, Tarras S (May 1992). “Brown-Sequard syndrome and herniated cervical disc”. 《Spine》 17 (5): 598–600. doi:10.1097/00007632-199205000-00022. PMID 1621163.

Hancock JB, Field EM, Gadam R (1997). “Spinal epidural hematoma progressing to Brown-Sequard syndrome: report of a case”. 《J Emerg Med》 15 (3): 309–12. doi:10.1016/S0736-4679(97)00010-3. PMID 9258779.

Harris P (November 2005). “Stab wound of the back causing an acute subdural haematoma and a Brown-Sequard neurological syndrome”. 《Spinal Cord》 43 (11): 678–9. doi:10.1038/sj.sc.3101765. PMID 15852056.

Henderson SO, Hoffner RJ (1998). “Brown-Sequard syndrome due to isolated blunt trauma”. 《J Emerg Med》 16 (6): 847–50. doi:10.1016/S0736-4679(98)00096-1. PMID 9848698.

Hwang W, Ralph J, Marco E, Hemphill JC (June 2003). “Incomplete Brown-Séquard syndrome after methamphetamine injection into the neck”. 《Neurology》 60 (12): 2015–6. doi:10.1212/01.wnl.0000068014.89207.99. PMID 12821761.

Kraus JA, Stüper BK, Berlit P (1998). “Multiple sclerosis presenting with a Brown-Séquard syndrome”. 《J. Neurol. Sci.》 156 (1): 112–3. doi:10.1016/S0022-510X(98)00016-1. PMID 9559998.

Lim E, Wong YS, Lo YL, Lim SH (April 2003). “Traumatic atypical Brown-Sequard syndrome: case report and literature review”. 《Clin Neurol Neurosurg》 105 (2): 143–5. doi:10.1016/S0303-8467(03)00009-X. PMID 12691810.

Lipper MH, Goldstein JH, Do HM (August 1998). “Brown-Séquard syndrome of the cervical spinal cord after chiropractic manipulation”. 《AJNR Am J Neuroradiol》 19 (7): 1349–52. PMID 9726481.

Mastronardi L, Ruggeri A (January 2004). “Cervical disc herniation producing Brown-Sequard syndrome: case report”. 《Spine》 29 (2): E28–31. doi:10.1097/01.BRS.0000105984.62308.F6. PMID 14722422.

Miyake S, Tamaki N, Nagashima T, Kurata H, Eguchi T, Kimura H (February 1998). “Idiopathic spinal cord herniation. Report of two cases and review of the literature”. 《J. Neurosurg.》 88 (2): 331–5. doi:10.3171/jns.1998.88.2.0331. PMID 9452246.

Rumana CS, Baskin DS (April 1996). “Brown-Sequard syndrome produced by cervical disc herniation: case report and literature review”. 《Surg Neurol》 45 (4): 359–61. doi:10.1016/0090-3019(95)00412-2. PMID 8607086.

Stephen AB, Stevens K, Craigen MA, Kerslake RW (October 1997). “Brown-Séquard syndrome due to traumatic brachial plexus root avulsion”. 《Injury》 28 (8): 557–8. doi:10.1016/S0020-1383(97)83474-2. PMID 9616398.

[4] Egido Herrero JA, Saldanã C, Jiménez A, Vázquez A, Varela de Seijas E, Mata P (1992). “Spontaneous cervical epidural hematoma with Brown-Séquard syndrome and spontaneous resolution. Case report”. 《J Neurosurg Sci》 36 (2): 117–9. PMID 1469473.

[5] Ellger T, Schul C, Heindel W, Evers S, Ringelstein EB (June 2006). “Idiopathic spinal cord herniation causing progressive Brown-Séquard syndrome”. 《Clin Neurol Neurosurg》 108 (4): 388–91. doi:10.1016/j.clineuro.2004.07.005. PMID 16483712.

[6] Finelli PF, Leopold N, Tarras S (May 1992). “Brown-Sequard syndrome and herniated cervical disc”. 《Spine》 17 (5): 598–600. doi:10.1097/00007632-199205000-00022. PMID 1621163.

[7] Hancock JB, Field EM, Gadam R (1997). “Spinal epidural hematoma progressing to Brown-Sequard syndrome: report of a case”. 《J Emerg Med》 15 (3): 309–12. doi:10.1016/S0736-4679(97)00010-3. PMID 9258779.

[8] Harris P (November 2005). “Stab wound of the back causing an acute subdural haematoma and a Brown-Sequard neurological syndrome”. 《Spinal Cord》 43 (11): 678–9. doi:10.1038/sj.sc.3101765. PMID 15852056.

[9] Henderson SO, Hoffner RJ (1998). “Brown-Sequard syndrome due to isolated blunt trauma”. 《J Emerg Med》 16 (6): 847–50. doi:10.1016/S0736-4679(98)00096-1. PMID 9848698.

[10] Hwang W, Ralph J, Marco E, Hemphill JC (June 2003). “Incomplete Brown-Séquard syndrome after methamphetamine injection into the neck”. 《Neurology》 60 (12): 2015–6. doi:10.1212/01.wnl.0000068014.89207.99. PMID 12821761.

[11] Kraus JA, Stüper BK, Berlit P (1998). “Multiple sclerosis presenting with a Brown-Séquard syndrome”. 《J. Neurol. Sci.》 156 (1): 112–3. doi:10.1016/S0022-510X(98)00016-1. PMID 9559998.

[12] Lim E, Wong YS, Lo YL, Lim SH (April 2003). “Traumatic atypical Brown-Sequard syndrome: case report and literature review”. 《Clin Neurol Neurosurg》 105 (2): 143–5. doi:10.1016/S0303-8467(03)00009-X. PMID 12691810.

[13] Lipper MH, Goldstein JH, Do HM (August 1998). “Brown-Séquard syndrome of the cervical spinal cord after chiropractic manipulation”. 《AJNR Am J Neuroradiol》 19 (7): 1349–52. PMID 9726481.

[14] Mastronardi L, Ruggeri A (January 2004). “Cervical disc herniation producing Brown-Sequard syndrome: case report”. 《Spine》 29 (2): E28–31. doi:10.1097/01.BRS.0000105984.62308.F6. PMID 14722422.

[15] Miyake S, Tamaki N, Nagashima T, Kurata H, Eguchi T, Kimura H (February 1998). “Idiopathic spinal cord herniation. Report of two cases and review of the literature”. 《J. Neurosurg.》 88 (2): 331–5. doi:10.3171/jns.1998.88.2.0331. PMID 9452246.

[16] Rumana CS, Baskin DS (April 1996). “Brown-Sequard syndrome produced by cervical disc herniation: case report and literature review”. 《Surg Neurol》 45 (4): 359–61. doi:10.1016/0090-3019(95)00412-2. PMID 8607086.

[17] Stephen AB, Stevens K, Craigen MA, Kerslake RW (October 1997). “Brown-Séquard syndrome due to traumatic brachial plexus root avulsion”. 《Injury》 28 (8): 557–8. doi:10.1016/S0020-1383(97)83474-2. PMID 9616398.

[1]

[2]

[3]

분류	D ICD-10: G83.8 ICD-9-CM: 344.89 MeSH: D018437 질병DB: 31117
외부 자원	EMedicine: emerg/70 pmr/17